Современные представления о гангренозной пиодермии


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Аннотация

В обзоре приводятся современные данные о гангренозной пиодермии - редком хроническом заболевании из группы нейтрофильных дерматозов. Рассмотрены вопросы патогенеза, связи с фоновой висцеральной патологией, особенности поражения кожи и внутренних органов. Даны главные и малые критерии диагностики, дифференцированные подходы к лечению.

Полный текст

Современные представления о гангренозной пиодермии. - Аннотация. В обзоре приводятся современные данные о гангренозной пиодермии - редком хроническом заболевании из группы нейтрофильных дерматозов. Рассмотрены вопросы патогенеза, связи с фоновой висцеральной патологией, особенности поражения кожи и внутренних органов. Даны главные и малые критерии диагностики, дифференцированные подходы к лечению.
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Об авторах

В Д Елькин

ГБОУ ВПО "Пермская государственная медицинская академия им. акад. Е.А. Вагнера" Минздрава России

Л С Митрюковский

ГБОУ ВПО "Пермская государственная медицинская академия им. акад. Е.А. Вагнера" Минздрава России

Е В Плотникова

ГБОУ ВПО "Пермская государственная медицинская академия им. акад. Е.А. Вагнера" Минздрава России

Email: elena.plotnikova@hotmail.com

Список литературы

  1. Ruocco E., Sangiuliano S., Gravina A.G. et al. Pyoderma gangrenosum: an updated review. J Eur Acad Dermatol Venereol 2009; 23 (9): 1008-1017.
  2. Лезвинская Е.М., Чилингиров Р.Х., Сухова Т.Е., Осипов А.В. К проблеме патогенеза и терапии гангренозной пиодермии. Рос журн кожн и вен бол 1998; 2: 41-44.
  3. Ahn B.K., Kim S.C. Pyodermatitis-pyostomatitis vegetans with circulating autoantibodies to bullous pemphigoid antigen 230. J Am Acad Dermatol 2004; 50 (5): 785-788.
  4. Andrade P., Brites M.M., Figueiredo A. Synchronous pyoderma gangrenosum and inflammatory bowel disease, healing after total proctocolectomy. An Bras Dermatol 2012; 87 (4): 637-639.
  5. Bhat R.M. Pyoderma gangrenosum: An update. Indian Dermatol Online J 2012; 3 (1): 7-13.
  6. Fox L.P., Geyer A.S., Husain S., Grossman M.E. Bullous pyoderma gangrenosum as the presenting sign of fatal acute myelogenous leukemia. Leuk Lymphoma 2006; 47 (1): 147-150.
  7. Sakamoto T., Hashimoto T., Furukawa F. Pyoderma gangrenosum in a patient with bullous systemic lupus erythematosus. Eur J Dermatol 2002; 12 (5): 485-487.
  8. Walsh M., Leonard N., Bell H. Superficial granulomatous pyoderma of the vulva in a patient receiving maintenance rituximab (MabThera) for lymphoma. J Low Genit Tract Dis 2011; 15 (2): 158-160.
  9. Albertazzi P., Di Micco R. Pyoderma gangrenosum of the cervix. Obstet Gynecol 2000; 96 (5, Pt 2): 825-826.
  10. Badgwell C., Rosen T. Penile pyoderma gangrenosum. Dermatol Online J 2006; 12 (2): 8.
  11. Melson M.R., Grossniklaus H.E., Murchison A.P. Pyoderma gangrenosum of the eyelids: recurrence in a skin graft. Ophthal Plast Reconstr Surg 2010; 26 (4): 295-297.
  12. Yuksel N., Ozdek S. Retinal vasculitis associated with pyoderma gangrenosum: a case report. J Ophthalmic Inflamm Infect 2012; 2 (4): 239-241.
  13. Mancini G.J., Floyd L., Solla J.A. Parastomal pyoderma gangrenosum: a case report and literature review. Am Surg 2002; 68 (9): 824-826.
  14. Williams S. Recognizing peristomal pyoderma gangrenosum. J Enterostomal Ther 1984; 11 (2): 77-79.
  15. Bryan C.S. Fatal pyoderma gangrenosum with pathergy after coronary artery bypass grafting. Tex Heart Inst J 2012; 39 (6): 894-897.
  16. Gibson L.E., Daoud M.S., Muller S.A., Perry H.O. Malignant pyodermas revisited. Mayo Clin Proc 1997; 72 (8): 734-736.
  17. Mantovani L., Zauli S., Sarno O. et al. Treatment of a relapsing facial pyoderma gangrenosum (malignant pyoderma). Int J Dermatol 2013; 52 (6): 753-756.
  18. Perry H.O., Winkelmann R.K., Muller S.A., Kierland R.R. Malignant pyodermas. Arch Dermatol 1968; 98 (6): 561-576.
  19. Wilson-Jones E., Winkelmann R.K. Superficial granulomatous pyoderma: a localized vegetative form of pyoderma gangrenosum. J Am Acad Dermatol 1988; 18 (3): 511-521.
  20. Cheung S.T., Zanetto U., Diaz C. Facial superficial granulomatous pyoderma treated with cyclosporin: not always a benign condition. Acta Derm Venereol 2006; 86 (4): 362-364.
  21. Dierick M., De Lille S., Claerhout I. et al. Superficial granulomatous pyoderma with ocular involvement. Eur J Dermatol 2010; 20 (5): 648-649.
  22. Gopi S.S., Evans A.T., Raza A., Byrne D.J. Superficial granulomatous pyoderma gangrenosum of the penis: a case report. Scientific World J 2007; 7: 2426-2429.
  23. Persing S.M., Laub D. Superficial granulomatous pyoderma of the face: a case report and review of the literature. Eplasty 2012; 12: e56.
  24. Matias Fde A., Rosa D.J., Carvalho M.T., Castañon M.C. Pyodermatitis-pyostomatitis vegetans: case report and review of medical literature. An Bras Dermatol 2011; 86 (4, Suppl. 1): S137-S140.
  25. Femiano F., Lanza A., Buonaiuto C. et al. Pyostomatitis vegetans: a review of the literature. Med Oral Patol Oral Cir Bucal 2009; 14 (3): E114-E117.
  26. Leibovitch I., Ooi C., Huilgol S.C. et al. Pyodermatitis-pyostomatitis vegetans of the eyelids case report and review of the literature. Ophthalmology 2005; 112 (10): 1809-1813.
  27. Nico M.M., Hussein T.P., Aoki V., Lourenço S.V. Pyostomatitis vegetans and its relation to inflammatory bowel disease, pyoderma gangrenosum, pyodermatitis vegetans, and pemphigus. J Oral Pathol Med 2012; 41 (8): 584-588.
  28. Ruiz-Roca J.A., Berini-Aytés L., Gay-Escoda C. Pyostomatitis vegetans. Report of two cases and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005; 99 (4): 447-454.
  29. Brinkmeier T., Frosch P.J. Pyodermatitis-pyostomatitis vegetans: a clinical course of two decades with response to cyclosporine and low-dose prednisolone. Acta Derm Venereol 2001; 81 (2): 134-136.
  30. Ko H.C., Jung D.S., Jwa S.W. et al. Two cases of pyodermatitis-pyostomatitis vegetans. J Dermatol 2009; 36 (5): 293-297.
  31. O'Loughlin S., Perry H.O. A diffuse pustular eruption associated with ulcerative colitis. Arch Dermatol 1978; 114 (7): 1061-1064.
  32. Chia M.W., Teo L., Tay Y.K., Poh W.T. Pustular pyoderma gangrenosum: an uncommon variant which is easily misdiagnosed. Dermatol Online J 2008; 14 (2): 21.
  33. Perry H.O., Winkelmann R.K. Bullous pyoderma gangrenosum and leukemia. Arch Dermatol 1972; 106 (6): 901-905.
  34. Altunay I.K., Sezgin S.A., Ileri U. et al. Atypical hemorrhagic bullous pyoderma gangrenosum. Int J Dermatol 2001; 40 (5): 327-329.
  35. Lewerin C., Mobacken H., Nilsson-Ehle H., Swolin B. Bullous pyoderma gangrenosum in a patient with myelodysplastic syndrome during granulocyte colony-stimulating factor therapy. Leuk Lymphoma 1997; 26 (5-6): 629-632.
  36. Marzano A.V., Trevisan V., Galloni C., Alessi E. Fatal bullous pyoderma gangrenosum in a patient with Klinefelter's syndrome. Acta Derm Venereol 2008; 88 (2): 158-159.
  37. Miyata T., Yashiro M., Hayashi M. et al. Bullous pyoderma gangrenosum of the bilateral dorsal hands. J Dermatol 2012; 39 (12): 1006-1009.
  38. Naik C.L., Singh G., Kumar L., Lokanatha K. Bullous pyoderma gangrenosum associated with ulcerative colitis. Indian J Dermatol Venerol Leprol 2008; 74 (1): 68-70.
  39. Newell E.L., Chaudhry S.I., Black M.M. Acute bullous hemorrhagic pyoderma gangrenosum: pitfalls of diagnostic delay. A case report. J Bone Joint Surg Am 2008; 90 (1): 174-177.
  40. Sheps M., Shapero H., Ramsay C. Bullous pyoderma gangrenosum and acute leukemia. Arch Dermatol 1978; 114 (12): 1842-1843.
  41. Wisaman D.H., Hunter H.J., Dennis M. Bullous pyoderma gangrenosum in acute myeloid leukaemia. Eur J Haematol 2007; 79 (1): 91-92.
  42. Елькин В.Д., Стекольников Г.А. Нейтрофильные дерматозы: проблемы диагностики на примере клинического случая. В сб. науч работ молодых ученых. Научная сессия ПГМА им. акад. Е.А. Вагнера. Пермь: ГБОУ ВПО ПГМА; 2013, 99-102.
  43. Jacobs J.C., Goetzl E.J. "Streaking leukocyte factor", arthritis, and pyoderma gangrenosum. Pediatrics 1975; 56 (4): 570-578.
  44. Lindor N.M., Arsenault T.M., Solomon H. et al. A new autosomal dominant disorder of pyogenic sterile arthritis, pyoderma gangrenosum, and acne: PAPA syndrome. Mayo Clin Proc 1997; 72 (7): 611-615.
  45. Demidowich A.P., Freeman A.F., Kuhns D.B. et al. Brief report: genotype, phenotype, and clinical course in five patients with PAPA syndrome (pyogenic sterile arthritis, pyoderma gangrenosum, and acne). Arthritis Rheum 2012; 64 (6): 2022-2027.
  46. Nesterovitch A.B., Hoffman M.D., Simon M. et al. Mutations in the PSTPIP1 gene and aberrant splicing variants in patients with pyoderma gangrenosum. Clin Exp Dermatol 2011; 36 (8): 889-895.
  47. Wise C.A., Gillum J.D., Seidman C.E. et al. Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder. Hum Mol Genet 2002; 11 (8): 961-969.
  48. Cortis E., De Benedetti F., Insalaco A. et al. Abnormal production of tumor necrosis factor (TNF) - alpha and clinical efficacy of the TNF inhibitor etanercept in a patient with PAPA syndrome. J Pediatr 2004; 145 (6): 851-855.
  49. Edrees A.F., Kaplan D.L., Abdou N.I. Pyogenic arthritis, pyoderma gangrenosum, and acne syndrome (PAPA syndrome) associated with hypogammaglobulinemia and elevated serum tumor necrosis factor-alpha levels. J Clin Rheumatol 2002; 8 (5): 273-275.
  50. Braun-Falco M., Kovnerystyy O., Lohse P., Ruzicka T. Pyoderma gangrenosum, acne, and suppurative hidradenitis (PASH) - a new autoinflammatory syndrome distinct from PAPA syndrome. J Am Acad Dermatol 2012; 66 (3): 409-415.
  51. Marzano A.V., Ishak R.S., Colombo A. et al. Pyoderma gangrenosum, acne and suppurative hidradenitis syndrome following bowel bypass surgery. Dermatology 2012; 225 (3): 215-219.
  52. Bruzzese V. Pyoderma gangrenosum, acne conglobata, suppurative hidradenitis, and axial spondyloarthritis: efficacy of anti-tumor necrosis factor α therapy. J Clin Rheumatol 2012; 18 (8): 413-415.
  53. García-Rabasco A.E., Esteve-Martínez A., Zaragoza-Ninet V. et al. Pyoderma gangrenosum associated with hidradenitis suppurativa: a case report and review of the literature. Actas Dermosifiliogr 2010; 101 (8): 717-721.
  54. Chahine B., Chenivesse C., Tillie-Leblond I. et al. Pulmonary manifestations of Pyoderma gangrenosum. Presse Med 2007; 36 (10, Pt 1): 1395-1395.
  55. Isomura I., Miyawaki S., Morita A. Pyoderma gangrenosum associated with nasal septal perforation, oropharyngeal ulcers and IgA paraproteinemia. J Dermatol 2005; 32 (3): 193-198.
  56. Paramkusam G., Meduri V., Gangeshetty N. Pyoderma gangrenosum with oral involvement - case report and review of the literature. Int J Oral Sci 2010; 2 (2): 111-116.
  57. Ahmed K., Ramsay B. Pyoderma gangrenosum associated with subcorneal pustular dermatosis and IgA myeloma. Clin Exp Dermatol 2009; 34 (1): 46-48.
  58. Aoussar A., Ismaïli N., Berbich L. et al. Pyoderma gangrenosum révélant une artérite de Takayasu. Ann Dermatol Venereol 2007; 134 (3): 264-267.
  59. Schmid M.H., Hary C., Marstaller B. et al. Pyoderma gangrenosum associated with the secondary antiphospholipid syndrome. Eur J Dermatol 1998; 8 (1): 45-47.
  60. Chiba T., Isomura I., Suzuki A., Morita A. Topical tacrolimus therapy for pyoderma gangrenosum. J Dermatol 2005; 32 (3): 199-203.
  61. Fonseka H.F., Ekanayake S.M., Dissanayake M. Two percent topical phenytoin sodium solution in treating pyoderma gangrenosum: a cohort study. Int Wound J 2010; 7 (6): 519-523.
  62. Hinterbergen L., Müller C.S., Vogt T., Pföhler C. Adalimumab: a treatment option for pyoderma gangrenosum after failure of systemic standard therapies. Dermatol Ther (Heidelb) 2012; 2 (1): 6.
  63. Kitayama A., Misago N., Okawa T. et al. Pyodermatitis-pyostomatitis vegetans after subtotal colectomy for ulcerative colitis. J Dermatol 2010; 38 (8): 714-717.
  64. Juillerat P., Christen-Zäch S., Troillet F.X. et al. Infliximab for the treatment of disseminated pyoderma gangrenosum associated with ulcerative colitis. Case report and literature review. Dermatology 2007; 215 (3): 245-251.
  65. Dobson C.M., Parslew R.A., Evans S. Superficial granulomatous pyoderma treated with intravenous immunoglobulin. J Am Acad Dermatol 2003; 48 (3): 456-460.
  66. Brenner M., Ruzicka T., Plewig G. et al. Targeted treatment of pyoderma gangrenosum in PAPA (pyogenic arthritis, pyoderma gangrenosum and acne) syndrome with the recombinant human interleukin-1 receptor antagonist anakinra. Br J Dermatol 2009; 161 (5): 1199-1201.
  67. Stichweh D.S., Punaro M., Pascual V. Dramatic improvement of pyoderma gangrenosum with infliximab in a patient with PAPA syndrome. Pediatr Dermatol 2005; 22 (3): 262-265.
  68. Елькин В.Д., Митрюковский Л.С., Седова Т.Г. Избранная дерматология. Редкие дерматозы и дерматологические синдромы. Пермь: ИПК "Звезда"; 2004.

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