Email this article Raltegravir is the first HIV integrase inhibitor as part of antiretroviral treatment regimens
- Authors: Kravchenko A.V.1, Kravchenko AV2
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Affiliations:
- Federal Research and Methodological Center for AIDS Prevention and Control, Central Research Institute of Epidemiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare
- Issue: Vol 82, No 11 (2010)
- Pages: 27-32
- Section: Editorial
- URL: https://ter-arkhiv.ru/0040-3660/article/view/30714
- ID: 30714
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Abstract
The paper gives the results of the largest international studies demonstrating the efficacy and safety of Raltegravir as part of antiretroviral treatment (ARVT) regimens in both patients starting therapy (STARTMRK study) and those pretreated with antiretroviral drugs (BENCHMRK study). The advantage of Raltegravir over Efavirens is the lower incidence of adverse central nervous system reactions.
Based on the results of published investigations, specialists from the USA and European Union have incorporated the first HIV integrase inhibitor Raltegravir into a first-line ARTV regimen. Raltegravir is the drug of choice and should be used in special categories of patients, such as those with chronic hepatitis C or fat metabolic disturbances.
Based on the results of published investigations, specialists from the USA and European Union have incorporated the first HIV integrase inhibitor Raltegravir into a first-line ARTV regimen. Raltegravir is the drug of choice and should be used in special categories of patients, such as those with chronic hepatitis C or fat metabolic disturbances.
About the authors
Aleksey Viktorovich Kravchenko
Email: kravchenko@hivrussia.net
A V Kravchenko
Federal Research and Methodological Center for AIDS Prevention and Control, Central Research Institute of Epidemiology, Russian Inspectorate for the Protection of Consumer Rights and Human WelfareFederal Research and Methodological Center for AIDS Prevention and Control, Central Research Institute of Epidemiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare
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