Первичные лимфопролиферативные заболевания центральной нервной системы


Цитировать

Полный текст

Аннотация

При первичных лимфомах ЦНС прогноз хуже, чем при других экстранодальных лимфомах: доля достижения ремиссий невелика, рецидивы развиваются очень часто. В работе проанализированы данные литературы по проблеме диагностики, определения факторов прогноза, перспектив и проблем лечения первичных лимфом ЦНС.

Об авторах

ндрей Владимирович Губкин

ГУ Гематологический научный центр РАМН

Email: gubkin@blood.ru
отделение ХГЗиИТ, врач отделения, к. м. н; ГУ Гематологический научный центр РАМН

Евгений Евгеньевич Звонков

ГУ Гематологический научный центр РАМН

Email: zvonkov@blood.ru
отд. химиотерапии гематологических заболеваний и интенсивной терапии, с. н. с., к. м. н; ГУ Гематологический научный центр РАМН

Александра Михайловна Кременецкая

ГУ Гематологический научный центр РАМН

Email: mtkalexandra@gmail.com
отд. ХГЗиИТ, зав. отделением; ГУ Гематологический научный центр РАМН

Сергей Кириллович Кравченко

ГУ Гематологический научный центр РАМН

Email: krav@blood.ru
отд. ХГЗиИТ, руководитель отделения; ГУ Гематологический научный центр РАМН

Андрей Иванович Воробьев

ГУ Гематологический научный центр РАМН

Email: nikita@blood.ru
директор, академик РАМН и РАН; ГУ Гематологический научный центр РАМН

A V Gubkin

E E Zvonkov

A M Kremenetskaya

S K Kravchenko

A I Vorobyev

Список литературы

  1. Russell D. S., Rubinstein L. J. Nervous system involvement by lymphomas, histiocytoses, and lenkemias. In: Pathology of tumours of the nervous system. 5-th ed. London: Edward Arnold; 1998. 195-237.
  2. Kadan-Lottick N. S., Skluzarek M. C., Gurney J. G. Decreasing incidence rates of primary central nervous system lymphoma. Cancer 2002; 95: 193-202.
  3. Henry J. M., Heffner R. R. J., Dillard S. H. et al. Primary malignant lymphomas of the central nervous system. Cancer 1974; 34: 1293-1302.
  4. O'Neill B. P., Illig J. J. Primary central nervous system lymphoma. Mayo Clin. Proc. 1989; 64: 1005-1020.
  5. Губкин А. В., Звонков Е. Е. и др. Первичные лимфопролиферативные заболевания центральной нервной системы. Клин. онкогематол. 2009; 1: 26-32.
  6. Iwamoto F. M., Abrey L. E. Primary dural lymphomas: a review. Neurosurg. Focus 2006; 21 (5): E5.
  7. Gobbato P. L., de Azambuja Pereira Filho A. et al. Primary meningeal burkitt-type lymphoma presenting as the first clinical manifestation of acquired immunodeficiency syndrome. Arq. Neuropsiquiatr. 2006; 64 (2-B): 511-515.
  8. Carole Soussain, Khe Hoang-Xuan, Doolittle N. D. New treatment approaches in pcnsl. Haematol Oncol. Clin. N. Am. 2005; 19: 719-728.
  9. Shah G. D., Yahalom J., Correa D. D. et al. Combined immunochemotherapy with reduced whole-brain radiotherapy for newly diagnosed primary CNS lymphoma. J. Clin. Oncol. Orig. Rep. 2007; 25 (30): 4730-4735.
  10. Miller D. C., Hochberg F. H., Harris N. L. et al. Pathology with clinical correlations of primary central nervous system non-Hodgkin's lymphoma. The Massachusetts General Hospital experience 1958-1998. Cancer 1998; 74: 1383-1397.
  11. MacMahon E. M. E., Glass J. D., Hayward S. D. et al. Epstein-Barr virus in AIDS-related primary central nervous system lymphoma. Lancet 1999; 338: 969-973.
  12. Ferreri A. J., Reni M., Villa E. Primary central nervous system lymphoma in immunocompetent patients. Cancer Treat. Rev. 1995; 21: 415-446.
  13. Bataille B., Delwail V., Menet E. et al. Primary intracerebral malignant lymphoma: A report of 248 cases. J. Neurosurg. 2000; 92: 261-266.
  14. Henson J. W., Batchelor T. T. Intraocular lymphoma. In: Batchelor T. T., ed. Lymphoma of the nervous system. Boston, MA: Butterworth-Heinemann; 2004. 183-188.
  15. Ferreri J. M., Blay J.-Y., Reni M. et al. Relevance of intraocular involvement in the management of primary central nervous system lymphomas. Ann. Oncol. 2002; 13: 531-538.
  16. Jellinger K. A., Paulus W. Primary central nervous system lymphomas-an update. J. Cancer Res. Clin. Oncol. 1992; 119: 7- 27.
  17. Hayakawa T., Takakura K., Abe H. et al. Primary central nervous system lymphoma in Japan - a retrospective, cooperative study by CNS-Lymphoma Study Group in Japan. J. Neurooncol. 1994; 19: 197-215.
  18. Fine H. A., Mayer R. J. Primary central nervous system lymphoma. Ann. Intern. Med. 1993; 119: 1093-1104.
  19. Воробьев А. И., Бриллиант М. Д. Лимфосаркомы. В кн.: Воробьев А. И. (ред.). Руководство по гематологии. М.: Медицина; 1985; т. 1: 336-337.
  20. Воробьев А. И., Кременецкая А. М. (ред.). Атлас. Опухоли лимфатической системы. М.: Ньюдиамед; 2007. 167-171.
  21. Гейманович З. И., Смирнов Л. И. Опухоли центральной нервной системы. Киев: Гос. мед. изд-во УССР; 1936.
  22. Jellinger K. A., Paulus W. Primary central nervous system lymphomas-new pathological developments. J. Neurooncol. 1995; 24: 33-36.
  23. Авцын А. П., Виккерт Т. М., Касумова С. Ю. Интернациональная гистологическая классификация опухолей центральной нервной системы. Журн. вопр. нейрохир. 1981; 2: 45-51.
  24. Keller A. R., Hochholzer L., Castleman B. Hyaline-vascular and plasma-cell types of giant lymph node hyperplasia of the mediastinum and other locations. Cancer 1972; 670-683.
  25. Schwechheimer K., Schwarzkopf G., Braus D. et al. Primary cerebral malignant non-Hodgkin's lymphomas. Histological and immunopathological findings on stereotactic brain biopsies. Clin. Neuropathol. 1989; 8: 250-251.
  26. Matano S., Nakamura S., Ohtake S. et al. Primary T-cell non-Hodgkin's lymphoma of the central nervous system. Case report and review of the literature. Acta Haematol. 1994; 91: 158-163.
  27. Lister A., Abrey L. E., Sandlund J. T. Central nervous system lymphoma. Hematology 2002; 1: 283-296.
  28. Hansen P. B., Penkowa M., Kirk O. et al. Human immunodeficiensy virus-associated malignant lymphoma in eastern Denmark diagnosed from 1990-1996: clinical features, histopathology, and association with Epstein-Barr virus and human herpesvirus-8. Eur. J. Haematol. 2000; 64: 368-375.
  29. Kumanishi T., Zhang S., Ichikawa T. et al. Primary malignant lymphoma of the brain: demonstration of frequent p16 and p15 gene deletions. Jpn J. Cancer Res. 1996; 87: 691-695.
  30. Reni M., Ferreri A. J., Zoldan M. C., Villa E. Primary brain lymphomas in patients with a prior or concomitant malignancy. J. Neurooncol. 1997; 32: 135-142.
  31. Воробьев А. И., Кременецкая А. М., Лорис Ю. Ю. и др. "Старые" и "новые" опухоли лимфатической системы. Тер. арх. 2000; 7: 9-14.
  32. Ferreri A. J., Reni M., Zoldan M. C. et al. Importance of complete staging in non-Hodgkin's lymphoma presenting as a cerebral mass lesion. Cancer 1996; 77: 827-833.
  33. Pollack I. F., Lunsford L. D., Flickinger J. C., Dameshek H. L. Prognostic factors in the diagnosis and treatment of primary central nervous system lymphoma. Cancer 1989; 63: 939-947.
  34. Ferreri A. J., Blay J. Y., Reni M. Prognostic scoring system for primary CNS lymphomas: the International Extranodal Lymphoma Study Group experience. J. Clin. Oncol. 2003; 21 (2): 266-272.
  35. Круглова Г. В., Абдулбаев Р. А., Финогенова И. А., Тарасюк С. В. Лечение и прогноз поражения центральной нервной системы при лимфосаркоме. Тер. арх. 1983; 55 (8): 36-40.
  36. Boiardi A., Sylvani A., Valentini S. et al. Chemotherapy as first treatment for primary malignant non-Hodgkin's lymphoma of the central nervous system preliminary data. J. Neurol. 1993; 241: 96-100.
  37. DeAngelis L. M., Yahalom J., Thaler H. T., Kher U. Combined modality therapy for primary CNS lymphoma. J. Clin. Oncol. 1992; 10: 635-643.
  38. Kikuchi K., Watanabe K., Miura S., Kowada M. Steroid-induced regression of primary malignant lymphoma of the brain. Surg. Neurol. 1996; 26: 291-296.
  39. DeAngelis L. M., Yahalom J., Heinemann M. H. et al. Primary CNS lymphoma: combined treatment with chemotherapy and radiotherapy. Neurology 1990; 40: 80-86.
  40. Shibamoto Y., Tsutsui K., Dodo Y. et al. Improved survival rate in primary intracranial lymphoma treated by high- dose radiation and systemic vincristine-doxorubicin-cyclophosphamide- prednisolone chemotherapy. Cancer 1990; 65: 1907-1912.
  41. Chamberlain M. C., Levin V. A. Adjuvant chemotherapy for primary lymphoma of the central nervous system. Arch. Neurol. 1990; 47: 1113-1116.
  42. Ferreri A. J., Reni M., Bolognesi A. et al. Combined therapy for primary central nervous system lymphoma in immunocompetent patients. Eur. J. Cancer 1995; 31 A: 2008-2012.
  43. Glass J., Gruber M. L., Cher L., Hochberg F. H. Preirradiation methotrexate chemotherapy of primary central nervous system lymphoma: long-term outcome. J. Neurosurg. 1994; 81: 188-195.
  44. Cher L., Glass J., Harsh G. R., Hochberg F. H. Therapy of primary CMS lymphoma with methotrexate-based chemotherapy and deferred radiotherapy: preliminary results. Neurology 1996; 46: 1757-1759.
  45. O'Brien P. C., Roos D. E., Liew K. H. et al. Preliminary results of combined chemotherapy and radiotherapy for non-AIDS primary central nervous system lymphoma. Trans-Tasman Radiation Oncology Group (TROG). Med. J. Aust. 1996; 165: 424-427.
  46. Guha-Thakurta N., Damek D., Pollack C., Hochberg F. H. Intravenous methotrexate as initial treatment for primary central nervous system lymphoma: response to therapy and quality of life of patients [In Process Citation]. J. Neurooncol. 1999; 43: 259-268.
  47. Blay J. Y., Bouhour D., Carrie C. et al. The C5R protocol: a regimen of high-dose chemotherapy and radiotherapy in primary cerebral non-Hodgkin's lymphoma of patients with no known cause of immunosuppression [see comments]. Blood 1995; 86: 2922-2929.
  48. Bessell E. M., Punt J., Firth J. et al. Primary non-Hodgkin's lymphoma of the central nervous system: phase II study of chemotherapy (BVAM) prior to radiotherapy. Clin. Oncol. (R. Coll. Radiol.) 1991; 3: 193-198.
  49. Glass J., Shustik C., Hochberg F. H. et al. Therapy of primary central nervous system lymphoma with pre-irradiation methotrexate, cyclophosphamide, doxorubicin, vincristine, and dexamethasone (MCHOD). J. Neurooncol. 1996; 30: 257-265.
  50. Korfel A., Thiel E. Successful treatment of non-Hodgkin's lymphoma of the central nervous system with BMPD chemotherapy followed by radiotherapy. Leukemia and Lymphoma. 1998; 30: 609-617.
  51. Brada M., Hjiyiannakis D., Hines F. et al. Short intensive primary chemotherapy and radiotherapy in sporadic primary CNS lymphoma (PCL). Int. J. Radiat. Oncol. Biol. Phys. 1998; 40: 1157-1162.
  52. Blay J. Y., Conroy T., Chevreau C. et al. High-dose methotrexate for the treatment of primary cerebral lymphomas: analysis of survival and late neurologic toxicity in a retrospective series. J. Clin. Oncol. 1998; 16: 864-871.
  53. O'Neill B. P., O'Fallon J. R., Earle J. D. et al. Primary central nervous system non-Hodgkin's lymphoma: survival advantages with combined initial therapy? [see comments]. Int. J. Radiat. Oncol. Biol. Phys. 1995; 33: 663-673.
  54. Schultz C., Scott C., Sherman W. et al. Preirradiation chemotherapy with cyclophospharnide, doxorubicin, vincristine, and dexamethasone for primary CMS lymphomas: initial report of radiation therapy oncology group protocol 88-06. J. Clin. Oncol. 1996; 14: 556-564.
  55. Bessell E. M., Graus F., Punt J. A. et al. Primary non-Hodgkin's lymphoma of the CNS treated with BVAM or CHOD/ BVAM chemotherapy before radiotherapy. J. Clin. Oncol. 1996; 14: 945-954.
  56. Camilleri-Broet S., Martin A., Moreau A. et al. Primary central nervous system lymphomas in 72 immunocompetent patients: pathologic findings and clinical correlations. Groupe Quest Est d'etude des Leucenies et Autres Maladies du Sang (GOELAMS). Am. J. Clin. Pathol. 1998; 110: 607-612.
  57. Dorreen M. S., Ironside J. W., Bradshaw J. D. et al. Primary intracerebral lymphoma: a clinicopathological analysis of 14 patients presenting over a 10-year period in Sheffield. Quart. J. Med. 1988; 67: 387-404.
  58. Davey P., Catton C., Ngan B., Whitton A. Phase I study of hyperfractionated whole brain irradiation (HWBI) in the treatment of primary cerebral lymphoma. Clin Oncol. (R. Coll. Radiol.) 1993; 5 (3): 159-164.
  59. Sandor V., Stark-Vanes V., Pearson D. et al. Phase II trial of chemotherapy alone for primary CNS and intraocular lymphoma. J. Clin. Oncol. 1998; 16: 3000-3006.
  60. Chamberlain M. C., Kormanik P. A., Barba D. Complications associated with intraventricular chemotherapy in patients with leptomeningeal metastases. J. Neurosurg. 1997; 87 (5): 694-699.
  61. Lishner M., Perrin R. G., Feld R. et al. Complications associated with Ommaya reservoirs in patients with cancer. The Princess Margaret Hospital experience and a review of the literature. Department of Medicine, Ontario Cancer Institute, Toronto, Canada. Arch. Intern. Med. 1990 Jan; 150 (1): 173-176.
  62. Gubkin A. et al. TioThepa, BCNU, VM-26, Dexamethasone, and High-dose Methotrexate (TioCaTeMeD) as therapy for Primary CNS Lymphoma (PCNSL). Ann. Oncol. 2002; 13 (suppl. 2: Abstract 8th International conference on malignant lymphoma): 125.
  63. Abrey L. E., Ben-Porat L., Panageas K. S. et al. Primary central nervous system lymphoma: The Memorial Sloan-Kettering Cancer Center Prognostic Model. J. Clin. Oncol. 2006; 24 (36): 5711-5715.
  64. Rubenstein I. L., Combs D., Kosenberg I. et al. Rituximab therapy for CNS lymphomas: targeting the leptomeningeal compartment. Blood 2003; 101 (2): 466-448.
  65. Pels H., Schulz H., Manzke O. et al. Intraventricular and intravenous treatment of a patient with refractory primary CNS lymphoma using rituximab. J. Neurooncol. 2002; 59 (3): 213-216.
  66. Gubkin A., Nikolaeva T. et al. Mabtera in the treatment of primary CNS lymphomas (PCNSL). Ann. Oncol. 2002; 13 (suppl. 2: Abstract 8-th International conference on malignant lymphoma): 125.

Дополнительные файлы

Доп. файлы
Действие
1. JATS XML
Скачать

© ООО "Консилиум Медикум", 2009

Creative Commons License
Эта статья доступна по лицензии Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
 

Адрес издателя

  • 127055, г. Москва, Алабяна ул., 13, корп.1

Адрес редакции

  • 127055, г. Москва, Алабяна ул., 13, корп.1

По вопросам публикаций

  • +7 (926) 905-41-26
  • editor@ter-arkhiv.ru

По вопросам рекламы

  • +7 (495) 098-03-59

 

  


Данный сайт использует cookie-файлы

Продолжая использовать наш сайт, вы даете согласие на обработку файлов cookie, которые обеспечивают правильную работу сайта.

О куки-файлах