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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">83298</article-id><article-id pub-id-type="doi">10.26442/00403660.2022.10.201906</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Reviews</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Intermittent fasting: endocrine aspects: A review</article-title><trans-title-group xml:lang="ru"><trans-title>Интервальное голодание: эндокринные аспекты</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5557-6742</contrib-id><name-alternatives><name xml:lang="en"><surname>Altashina</surname><given-names>Marina V.</given-names></name><name xml:lang="ru"><surname>Алташина</surname><given-names>Марина Викторовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>канд. мед. наук, науч. сотр. отд-ния вспомогательных репродуктивных технологий ФГБУ «НМИЦ эндокринологии»</p></bio><email>alt-mar@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2764-1049</contrib-id><name-alternatives><name xml:lang="en"><surname>Ivannikova</surname><given-names>Ekaterina V.</given-names></name><name xml:lang="ru"><surname>Иванникова</surname><given-names>Екатерина Владимировна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>канд. мед. наук, ст. науч. сотр. лаб. возрастных метаболических и эндокринных нарушений ОСП «Российский геронтологический научно-клинический центр» ФГАОУ ВО «РНИМУ им. Н.И. Пирогова»</p></bio><email>doc.ivannikova@gmail.com</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8520-8702</contrib-id><name-alternatives><name xml:lang="en"><surname>Troshina</surname><given-names>Ekaterina A.</given-names></name><name xml:lang="ru"><surname>Трошина</surname><given-names>Екатерина Анатольевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>чл.-кор. РАН, д-р мед. наук, проф., зам. дир. – дир. Института клинической эндокринологии ФГБУ «НМИЦ эндокринологии»</p></bio><email>troshina@inbox.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">National Medical Research Center for Endocrinology</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр эндокринологии» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Pirogov Russian National Research Medical University</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2022-11-22" publication-format="electronic"><day>22</day><month>11</month><year>2022</year></pub-date><volume>94</volume><issue>10</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>1182</fpage><lpage>1187</lpage><history><date date-type="received" iso-8601-date="2021-10-18"><day>18</day><month>10</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/83298">https://ter-arkhiv.ru/0040-3660/article/view/83298</self-uri><abstract xml:lang="en"><p>The increasing number of overweight and obese people makes the search for new effective ways to reduce body weight extremely urgent. Recently, intermittent fasting has received a lot of attention, as a dietary protocol, presumably effective in reducing body weight. Despite the large number of studies, the effects of intermittent fasting on the human body are controversial, since studies differ in dietary options, design, and often have a small sample size. In this review of the literature, the authors cite the results of studies of the effectiveness of intermittent fasting in patients with obesity, diabetes mellitus, and high risks of developing cardiovascular diseases.</p></abstract><trans-abstract xml:lang="ru"><p>Ежегодно увеличивающееся число лиц с избыточной массой тела и ожирением делает поиск новых эффективных способов снижения массы тела крайне актуальным. В последнее время большое внимание привлекает интервальное голодание в качестве диетического протокола, предположительно эффективного при снижении массы тела. Несмотря на большое число работ, последствия применения интервального голодания на организм человека спорны, поскольку исследования отличаются между собой вариантами рациона, дизайном и часто имеют небольшой размер выборки. В данном обзоре литературы авторы приводят результаты исследований эффективности интервального голодания у пациентов с ожирением, сахарным диабетом, высокими рисками развития сердечно-сосудистых заболеваний.</p></trans-abstract><kwd-group xml:lang="en"><kwd>intermittent fasting</kwd><kwd>obesity</kwd><kwd>adipose tissue</kwd><kwd>dyslipidemia</kwd><kwd>insulin resistance</kwd><kwd>diabetes mellitus</kwd><kwd>cardiovascular disease</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>интервальное голодание</kwd><kwd>ожирение</kwd><kwd>жировая ткань</kwd><kwd>дислипидемия</kwd><kwd>инсулинорезистентность</kwd><kwd>сахарный диабет</kwd><kwd>сердечно- сосудистые заболевания</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Flegal KM, Kruszon-Moran D, Carroll MD, et al. Trends in obesity among adults in the united states, 2005 to 2014. JAMA. 2016;315:2284-91. 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