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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">71138</article-id><article-id pub-id-type="doi">10.26442/00403660.2021.04.200673</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Editorial article</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Передовая статья</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Nuclear medicine and molecular imaging in clinical practice: yesterday, today and tomorrow</article-title><trans-title-group xml:lang="ru"><trans-title>Ядерная медицина и молекулярная визуализация в клинической практике: вчера, сегодня, завтра</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0487-6902</contrib-id><name-alternatives><name xml:lang="en"><surname>Sergienko</surname><given-names>Vladimir B.</given-names></name><name xml:lang="ru"><surname>Сергиенко</surname><given-names>Владимир Борисович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>doctor of medical sciences, prof., hands. dep. radionuclide diagnostics and PET</p></bio><bio xml:lang="ru"><p>д.м.н., проф., рук. отд. радионуклидной диагностики и ПЭТ</p></bio><email>a.ansheles@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2675-3276</contrib-id><name-alternatives><name xml:lang="en"><surname>Ansheles</surname><given-names>Aleksei A.</given-names></name><name xml:lang="ru"><surname>Аншелес</surname><given-names>Алексей Аркадьевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Doctor of Medical Sciences, Art. scientific. employee of the department of radionuclide diagnostics and PET</p></bio><bio xml:lang="ru"><p>д.м.н., ст. науч. сотрудник отделения радионуклидной диагностики и ПЭТ</p></bio><email>a.ansheles@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">National Medical Research Center of Cardiology</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр кардиологии» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2021-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2021</year></pub-date><volume>93</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>357</fpage><lpage>362</lpage><history><date date-type="received" iso-8601-date="2021-05-31"><day>31</day><month>05</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-05-31"><day>31</day><month>05</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2021, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2021, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/71138">https://ter-arkhiv.ru/0040-3660/article/view/71138</self-uri><abstract xml:lang="en"><p>Over the past 40 years, nuclear medicine has grown to be the largest non-invasive diagnostic and therapeutic industry in the world, playing a pivotal role in various fields and disciplines of clinical practice and contributing to improved quality of life and patient prognosis. Over the first 20 years of the XXI century, the number of radionuclide procedures in the world has increased significantly, primarily due to innovations in radiopharmaceuticals, continuous improvement of the technical properties of equipment and the expansion of the boundaries of multimodal imaging. The review examines the historical and current trends in the development of nuclear medicine in the world and in Russia, including those related to radionuclide diagnostics, therapy and theranostics.</p></abstract><trans-abstract xml:lang="ru"><p>За последние 40 лет ядерная медицина превратилась в крупнейшую отрасль неинвазивной диагностики и терапии в мире, играя важнейшую роль в различных сферах и дисциплинах клинической практики и способствуя улучшению качества жизни и прогноза пациентов. За первые 20 лет XXI в. количество радионуклидных процедур в мире значительно увеличилось, в первую очередь благодаря инновациям в радиофармацевтике, постоянному улучшению технических свойств оборудования и расширению границ применения мультимодальной визуализации. В обзоре рассматриваются исторические и современные тенденции развития ядерной медицины в мире и России, в том числе касательно радионуклидной диагностики, терапии и тераностики.</p></trans-abstract><kwd-group xml:lang="en"><kwd>nuclear medicine</kwd><kwd>radionuclide diagnostics</kwd><kwd>radionuclide therapy</kwd><kwd>theranostics</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>ядерная медицина</kwd><kwd>радионуклидная диагностика</kwd><kwd>радионуклидная терапия</kwd><kwd>тераностика</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Hevesy G. 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