Terapevticheskii arkhivTerapevticheskii arkhivТерапевтический архив0040-36602309-5342LLC Obyedinennaya Redaktsiya69056210.26442/00403660.2026.03.203545ReviewsОбзорыReview ArticlePulmometabolic syndrome: a reviewПульмометаболический синдромhttps://orcid.org/0000-0002-0206-6420BakharevaTatiana A.БахареваТатьяна Александровна
Russian Federation

ассистент, аспирант каф. госпитальной терапии Института материнства и детства

baharevatatyana3@gmail.comhttps://orcid.org/0009-0006-7554-5787BelovAlexander M.БеловАлександр Михайлович
Russian Federation

д-р мед. наук, проф., зав. каб. сомнологии

baharevatatyana3@gmail.comhttps://orcid.org/0000-0002-8899-4294GorbunkovStanislav D.ГорбунковСтанислав Дмитриевич
Russian Federation

д-р мед. наук, доц., глав. врач

baharevatatyana3@gmail.comhttps://orcid.org/0000-0003-1884-6349YusupovArthur I.ЮсуповАртур Ильдусович
Russian Federation

канд. мед. наук, зав. отд-нием сердечно-сосудистой хирургии

baharevatatyana3@gmail.comhttps://orcid.org/0000-0002-2469-7346BaranovaIrina A.БарановаИрина Александровна
Russian Federation

д-р мед. наук, проф. каф. госпитальной терапии Института материнства и детства

baharevatatyana3@gmail.comPirogov Russian National Research Medical University (Pirogov University)ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России (Пироговский Университет)United Hospital with a PolyclinicФГБУ «Объединенная больница с поликлиникой» Управления делами Президента РФResearch Institute of PulmonologyФГБУ «Научно-исследовательский институт пульмонологии» ФМБА России17032026983Issues of pulmonologyВопросы пульмонологии1831882109202526122025Copyright ©; 2026, Consilium MedicumCopyright ©; 2026, ООО "Консилиум Медикум"2026Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc-sa/4.0https://ter-arkhiv.ru/0040-3660/article/view/690562

In this review, we discuss the underexplored issue of the relationship between metabolic syndrome (MS) and respiratory diseases. The review discusses the main pathogenic mechanisms, including chronic low-grade inflammation, oxidative stress, endothelial dysfunction, and mechanical restriction of lung volumes. The concept of pulmonometabolic syndrome is introduced. Data of the results of studies of the functional parameters of the lungs in MS are presented. We describe the clinical and pathobiological characteristics of the mutually aggravating interaction between MS and respiratory disorders, such as chronic obstructive pulmonary disease, bronchial asthma, obstructive sleep apnea, lung cancer, and pulmonary hypertension.

В обзоре обсуждается малоизученная проблема взаимосвязи метаболического синдрома (МС) и заболеваний органов дыхания. Рассматриваются основные патогенетические механизмы, включая хроническое низкоинтенсивное воспаление, окислительный стресс, эндотелиальную дисфункцию, механическое ограничение легочных объемов. Вводится понятие «пульмометаболический синдром». Приводятся данные результатов исследований функциональных показателей легких при МС. Описываются клинические и патобиологические характеристики взаимоотягощающей связи МС с патологиями органов дыхания, такими как хроническая обструктивная болезнь легких, бронхиальная астма, синдром обструктивного апноэ во время сна, рак легкого, легочная гипертензия.

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