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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">64879</article-id><article-id pub-id-type="doi">10.26442/00403660.2021.02.200612</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>History of medicine</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>История медицины</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Historical milestones in the knowledge of celiac disease: on the 80th anniversary of the discovery of W.-K. Dike of the аgluten diet</article-title><trans-title-group xml:lang="ru"><trans-title>Исторические вехи познания целиакии: к 80-летию открытия В.-К. Дике аглютеновой диеты</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9782-4860</contrib-id><name-alternatives><name xml:lang="en"><surname>Parfenov</surname><given-names>A. I.</given-names></name><name xml:lang="ru"><surname>Парфенов</surname><given-names>Асфольд Иванович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>д.м.н., проф., зав. отд. патологии кишечника ГБУЗ «МКНЦ им. А.С. Логинова»</p></bio><email>asfold@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Loginov Moscow Clinical Research and Practical</institution></aff><aff><institution xml:lang="ru">ГБУЗ «Московский клинический научный центр им. А.С. Логинова» Департамента здравоохранения г. Москвы</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2021-02-15" publication-format="electronic"><day>15</day><month>02</month><year>2021</year></pub-date><volume>93</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>243</fpage><lpage>248</lpage><history><date date-type="received" iso-8601-date="2021-04-06"><day>06</day><month>04</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-04-06"><day>06</day><month>04</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2021, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2021, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/64879">https://ter-arkhiv.ru/0040-3660/article/view/64879</self-uri><abstract xml:lang="en"><p>The article describes the main achievements in the knowledge of celiac disease – a mysterious disease known since the time of Hippocrates. The most important discovery was made by Willem-Karel Dicke, in 1941 linking the cause of the disease with the consumption of bread. Dicke is recognized as an outstanding medical worker in Holland. His memory and contribution to medicine is embodied in the Dicke Medal, the most prestigious award of the Dutch Society of Gastroenterology.</p></abstract><trans-abstract xml:lang="ru"><p>В статье описаны основные достижения в познании целиакии – загадочной болезни, известной со времен Гиппократа. Самое главное открытие сделал Виллем-Карел Дике, связав в 1941 г. причину болезни с употреблением хлеба. Дике признан выдающимся деятелем медицины Голландии. Его память и вклад в медицину воплощены в медали Дике – самой престижной награде Голландского общества гастроэнтерологов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>celiac disease</kwd><kwd>gluten</kwd><kwd>Gee–Herter–Heibner disease</kwd><kwd>W.-K. Dicke</kwd><kwd>tropical sprue</kwd><kwd>idiopathic steatorrhea</kwd><kwd>Crosby capsule</kwd><kwd>small intestine enzymes</kwd><kwd>cytoprotector rebamipide</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>целиакия</kwd><kwd>глютен</kwd><kwd>болезнь Джи–Гертера–Гейбнера</kwd><kwd>В.-К. Дике</kwd><kwd>тропическая спру</kwd><kwd>идиопатическая стеаторея</kwd><kwd>капсула Кросби</kwd><kwd>ферменты тонкой кишки</kwd><kwd>цитопротектор ребамипид</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Fasano A. Celiac Disease – How to Handle a Clinical Chameleon. NEJM. 2003;348:2568-70.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>McManus R, Kelleher D. Celiac Disease – The Villain Unmasked? NEJM. 2003;348:2573-4.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Энциклопедический словарь медицинских терминов. Т. 3. Под ред. Б.В. Петровского. 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