Terapevticheskii arkhivTerapevticheskii arkhivТерапевтический архив0040-36602309-5342LLC Obyedinennaya Redaktsiya62297510.26442/00403660.2023.09.202400ReviewsОбзорыReview ArticleSacubitril/valsartan in patients with mildly reduced or preserved ejection fraction and worsening heart failure: A reviewСакубитрил/валсартан у пациентов с умеренно сниженной или сохраненной фракцией выброса и ухудшением сердечной недостаточностиhttps://orcid.org/0000-0002-4066-2661ZhirovIgor V.ЖировИгорь Витальевич
Russian Federation

Medicorum Scientiarum Doctor, Investigator Princeps Department of Morborum Myocardialium et Cordis Defectus, Professor Department of Cardiologiae

доктор медицинских наук, ведущий научный сотрудник отделения заболеваний миокарда и сердечной недостаточности, профессор кафедры кардиологии

izhirov@mail.ruhttps://orcid.org/0000-0001-6624-3804SafronovaNatalia V.СафроноваНаталия Владимировна
Russian Federation

Candidatus Scientiarum Medical, Junior Investigator, Department of Myocardial Morborum et Cordis Defectus

кандидат медицинских наук, младший научный сотрудник отделения заболеваний миокарда и сердечной недостаточности

izhirov@mail.ruhttps://orcid.org/0000-0001-9234-6129TereshchenkoSergey N.ТерещенкоСергей Николаевич
Russian Federation

Doctor of Medical Sciences, Professor, Head of Department myocardial diseases and heart failure

доктор медицинских наук, профессор, руководитель отд. заболеваний миокарда и сердечной недостаточности

izhirov@mail.ruChazov National Medical Research Center of CardiologyФГБУ «Национальный медицинский исследовательский центр кардиологии имени акад. Е.И. Чазова» Минздрава РоссииRussian Medical Academy of Continuous Professional EducationФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России031120239598028090411202304112023Copyright ©; 2023, Consilium MedicumCopyright ©; 2023, ООО "Консилиум Медикум"2023Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc-sa/4.0https://ter-arkhiv.ru/0040-3660/article/view/622975

Heart failure with mildly reduced ejection fraction and heart failure with preserved ejection fraction are associated with significant morbidity and mortality, as well as growing economic burden. This review describes recent studies on the use of sacubitril/valsartan in heart failure patients with mildly reduced or preserved ejection fraction.

Сердечная недостаточность с умеренно сниженной фракцией выброса и сердечная недостаточность с сохраненной фракцией выброса связаны со значительной заболеваемостью и смертностью, а также с растущим экономическим бременем. В обзоре представлено описание последних исследований по применению сакубитрила/валсартана у пациентов с сердечной недостаточностью с умеренно сниженной или сохраненной фракцией выброса.

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