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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">595875</article-id><article-id pub-id-type="doi">10.26442/00403660.2024.04.202683</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Reviews</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">4D flow MRI: value and clinical perspectives in patients with pathology of the heart and great vessels. A review</article-title><trans-title-group xml:lang="ru"><trans-title>4D МР-визуализация потока: ценность и клинические перспективы у пациентов с патологией сердца и магистральных сосудов</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7780-2405</contrib-id><name-alternatives><name xml:lang="en"><surname>Yurpolskaya</surname><given-names>Lyudmila A.</given-names></name><name xml:lang="ru"><surname>Юрпольская</surname><given-names>Людмила Анатольевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>д-р мед. наук, вед. науч. сотр. рентген-диагностического отд.</p></bio><email>layurpolskaya@bakulev.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Bakoulev National Medical Research Center for Cardiovascular Surgery</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр сердечно-сосудистой хирургии им. А.Н. Бакулева» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2024-05-02" publication-format="electronic"><day>02</day><month>05</month><year>2024</year></pub-date><volume>96</volume><issue>4</issue><issue-title xml:lang="en">Issues of diagnostics of internal diseases</issue-title><issue-title xml:lang="ru">Вопросы диагностики внутренних болезней</issue-title><fpage>391</fpage><lpage>395</lpage><history><date date-type="received" iso-8601-date="2023-09-26"><day>26</day><month>09</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2024-04-16"><day>16</day><month>04</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/595875">https://ter-arkhiv.ru/0040-3660/article/view/595875</self-uri><abstract xml:lang="en"><p>The study of blood flow is becoming a new trend in cardiology and cardiovascular surgery. Based on the literature and our own data, a review is presented on the use of 4D flow in diseases of the heart and blood vessels. The main state of the question about the features of the application of the technique in various pathologies of the cardiovascular system is described in detail, the priorities, limitations and promising directions of the technique application are considered taking into account the goals of practical medicine. The review consists of two parts. The first is devoted to general issues, limitations of the technique, and issues of 4D flow mapping in patients with lesions of the great vessels. In the second part, the emphasis is on the use of 4D flow magnetic resonance imaging in the study of intraventricular blood flow and the application of the technique in congenital heart and vascular diseases.</p></abstract><trans-abstract xml:lang="ru"><p>Изучение кровотока становится новым трендом в кардиологии и сердечно-сосудистой хирургии. На основе литературных и собственных данных представлен обзор по применению 4D-магнитно-резонансной визуализации потока (4D flow) при заболеваниях сердца и сосудов. Подробно изложены особенности применения методики при разных патологиях сердечно-сосудистой системы, рассмотрены приоритеты, ограничения и перспективные направления использования методики с учетом целей практической медицины. Обзор состоит из двух частей. Первая посвящена общим вопросам, ограничениям методики и 4D-картированию потока у пациентов с поражением магистральных сосудов. Во второй части акцент сделан на использование 4D магнитно-резонансного томографического потока при изучении внутрижелудочкового кровотока и применение методики при врожденных пороках сердца и сосудов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>4D flow</kwd><kwd>cardiovascular diseases</kwd><kwd>hemodynamics</kwd><kwd>magnetic resonance imaging</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>4D-визуализация потока</kwd><kwd>заболевания сердца и сосудов</kwd><kwd>гемодинамика</kwd><kwd>магнитно-резонансная томография</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Takehara Y. 4D Flow when and how? Radiol Med. 2020;125(9):838-50. DOI:10.1007/s11547-020-01249-0</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Itatani K, Sekine T, Yamagishi M, et al. Hemodynamic Parameters for Cardiovascular System in 4D Flow MRI: Mathematical Definition and Clinical Applications. 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