Terapevticheskii arkhivTerapevticheskii arkhiv0040-36602309-5342LLC Obyedinennaya Redaktsiya5691210.26442/00403660.2020.11.000417Research ArticleWhooping cough in different periods of pregnancyPopovaO. P.doctorpopova@yandex.ruhttps://orcid.org/0000-0002-1772-5978SmetaninaS. V.doctorpopova@yandex.ruAntipyatN. A.doctorpopova@yandex.ruRevazyanN. R.doctorpopova@yandex.ruSkirdaT. A.doctorpopova@yandex.ruRussian Medical Academy of Continuous Professional EducationInfectious Clinical Hospital №1Gabrichevsky Moscow Research Institute of Microbiology and Epidemiology15112020921113162512202025122020Copyright © 2020, Consilium Medicum2020<p><strong>Aim. </strong>To study the clinical course, diagnosis of pertussis in pregnant women.</p>
<p><strong>Materials and methods. </strong>Under observation were 25 pregnant women with whooping cough. The age structure was dominated by patients from 6 to 35 years old, amounting to 64%. At the time of hospitalization in 2 (8%) patients the gestation period corresponded to the first trimester, in 7 (28%) II, in 9 (36%) III. In 7 (28%) patients, the diagnosis of whooping cough was made during childbirth. The following methods were used to verify pertussis: bacteriological, PCR and serological (ELISA).</p>
<p><strong>Results and discussion. </strong>Clinical analysis showed that pregnant women with pertussis who came to the hospital were admitted to hospital mainly in the late stages of the disease (at 45 week in 68.6% of cases). Pertussis infection in all cases was typical: in moderate form 96%, mild at 4%. In 64% of patients, whooping cough accompanied by other respiratory diseases, which were the main cause of development of bronchitis. The use of ELISA allowed to confirm the clinical diagnosis in 91.7% of patients.</p>
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