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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">46857</article-id><article-id pub-id-type="doi">10.26442/00403660.2020.09.000558</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Reviews</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Hypertrophic cardiomyopathy in elderly: causes, diagnostic and treatment approaches</article-title><trans-title-group xml:lang="ru"><trans-title>Гипертрофическая кардиомиопатия у пожилых: причины, диагностика, лечение</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2373-1183</contrib-id><name-alternatives><name xml:lang="en"><surname>Chumakova</surname><given-names>O. S.</given-names></name><name xml:lang="ru"><surname>Чумакова</surname><given-names>Ольга Сергеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>к.м.н., доц. каф. терапии, кардиологии и функциональной диагностики с курсом нефрологии</p></bio><email>chumakovaolga@bk.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Central State Medical Academy of the President of the Russian Federation</institution></aff><aff><institution xml:lang="ru">ФГБУ ДПО «Центральная государственная медицинская академия» Управления делами Президента РФ</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2020-10-14" publication-format="electronic"><day>14</day><month>10</month><year>2020</year></pub-date><volume>92</volume><issue>9</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>63</fpage><lpage>69</lpage><history><date date-type="received" iso-8601-date="2020-10-13"><day>13</day><month>10</month><year>2020</year></date><date date-type="accepted" iso-8601-date="2020-10-13"><day>13</day><month>10</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2020, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2020, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/46857">https://ter-arkhiv.ru/0040-3660/article/view/46857</self-uri><abstract xml:lang="en"><p>Hypertrophic cardiomyopathy is the most common inherited heart disorder with high clinical heterogeneity. Every fifth patient is older than 60 years at first diagnosis. This review discusses the possible causes for the late onset of hypertrophic cardiomyopathy, the diagnostic and treatment approaches in the elderly.</p></abstract><trans-abstract xml:lang="ru"><p>Гипертрофическая кардиомиопатия (ГКМП) – самая распространенная наследственная патология сердца с высокой клинической гетерогенностью. У каждого пятого больного диагноз впервые устанавливается в возрасте старше 60 лет. В обзоре обсуждаются возможные причины позднего дебюта гипертрофической кардиомиопатии, особенности диагностики и лечения этого заболевания у пожилых больных.</p></trans-abstract><kwd-group xml:lang="en"><kwd>hypertrophic cardiomyopathy</kwd><kwd>elderly</kwd><kwd>genetics</kwd><kwd>diagnostics</kwd><kwd>treatment</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>гипертрофическая кардиомиопатия</kwd><kwd>пожилые</kwd><kwd>генетика</kwd><kwd>диагностика</kwd><kwd>лечение</kwd></kwd-group><funding-group><funding-statement xml:lang="en">Grant from the Russian Science Foundation No. 20-15-00353</funding-statement><funding-statement xml:lang="ru">Грант Российского научного фонда №20-15-00353</funding-statement></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Elliott PM, Anastasakis A, Borger MA, et al. 2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy. 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