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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">32901</article-id><article-id pub-id-type="doi">10.26442/terarkh201890104-93</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Editorial article</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Передовая статья</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Reproductive disorders, osteoporosis and secondary hyperparathyroidism with celiac disease</article-title><trans-title-group xml:lang="ru"><trans-title>Репродуктивные расстройства, остеопороз и вторичный гиперпаратиреоз при целиакии</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Krums</surname><given-names>L M</given-names></name><name xml:lang="ru"><surname>Крумс</surname><given-names>Лариса Матисовна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., с.н.с. отд-ния невоспалительной патологии кишечника</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bykova</surname><given-names>S V</given-names></name><name xml:lang="ru"><surname>Быкова</surname><given-names>Светлана Владимировна</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., зав. отд-нием невоспалительной патологии кишечника</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sabelnikova</surname><given-names>E A</given-names></name><name xml:lang="ru"><surname>Сабельникова</surname><given-names>Елена Анатольевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., зам. директора по научной работе</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Aminova</surname><given-names>Ts V</given-names></name><name xml:lang="ru"><surname>Амнинова</surname><given-names>Ц В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Poleva</surname><given-names>N I</given-names></name><name xml:lang="ru"><surname>Полева</surname><given-names>Наталья Ивановна</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., н.с. отд-ния невоспалительной патологии кишечника</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gudkov</surname><given-names>R B</given-names></name><name xml:lang="ru"><surname>Гудкова</surname><given-names>Раиса Борисовна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., с.н.с. лаб. научно-диагностических исследований</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Turaeva</surname><given-names>M B</given-names></name><name xml:lang="ru"><surname>Тураева</surname><given-names>Мунавар Бурхоновна</given-names></name></name-alternatives><bio xml:lang="ru"><p>патологоанатом</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Parfenov</surname><given-names>A I</given-names></name><name xml:lang="ru"><surname>Парфенов</surname><given-names>Асфольд Иванович</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., проф., зав. отд. патологии кишечника</p></bio><email>asfold@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">A.S. Loginov Moscow Clinical Scientific Practical Center of the Moscow Healthcare Department</institution></aff><aff><institution xml:lang="ru">ГБУЗ «Московский клинический научно-практический центр им. А.С. Логинова Департамента здравоохранения Москвы»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2018-10-15" publication-format="electronic"><day>15</day><month>10</month><year>2018</year></pub-date><volume>90</volume><issue>10</issue><issue-title xml:lang="en">VOL 90, NO10 (2018)</issue-title><issue-title xml:lang="ru">ТОМ 90, №10 (2018)</issue-title><fpage>89</fpage><lpage>93</lpage><history><date date-type="received" iso-8601-date="2020-04-11"><day>11</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2018, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2018, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/32901">https://ter-arkhiv.ru/0040-3660/article/view/32901</self-uri><abstract xml:lang="en"><p>A clinical observation of a patient with celiac disease, aged 23, with severe form of osteoporosis, accompanied by atraumatic fractures bones, lameness, late onset of menstruation and pathology of pregnancy is described. It is emphasized that only a timely diagnosis celiac disease and timely prescribed treatment make it possible to avoid severe complications.</p></abstract><trans-abstract xml:lang="ru"><p>Описано клиническое наблюдение больной целиакией, 23 лет, с тяжелой формой остеопороза, сопровождавшегося атравматичными переломами костей, хромотой, поздним началом менструаций и патологией беременностей. Подчеркивается, что только вовремя установленный диагноз целиакии и своевременно назначенное лечение дают возможность избежать тяжелых осложнений.</p></trans-abstract><kwd-group xml:lang="en"><kwd>typical celiac disease</kwd><kwd>osteoporosis</kwd><kwd>atraumatic fracture of bones</kwd><kwd>reproductive disorders</kwd><kwd>gluten-free diet</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>типичная целиакия</kwd><kwd>остеопороз</kwd><kwd>атравматический перелом костей</kwd><kwd>репродуктивные расстройства</kwd><kwd>аглютеновая диета</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Парфенов А.И., Быкова С.В., Сабельникова Е.А., Крумс Л.М. и др. Российский консенсус по диагностике и лечению целиакии у детей и взрослых. Терапевтический архив. 2017;89(3)94-107. doi: 10.17116/terarkh201789394-107</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Nadhem O.N, Azeez G, Smalligan R.D, et al. 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