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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">32506</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Editorial article</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Передовая статья</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Three cases of late syphilitic hepatitis</article-title><trans-title-group xml:lang="ru"><trans-title>Три случая позднего сифилитического гепатита</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Loseva</surname><given-names>O K</given-names></name><name xml:lang="ru"><surname>Лосева</surname><given-names>Ольга Казимировна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., проф., эксперт по вопросам диагностики, клиники и лечения сифилиса и других ИПППП</p></bio><email>loseva_ok@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Dergacheva</surname><given-names>I A</given-names></name><name xml:lang="ru"><surname>Дергачёва</surname><given-names>Ирина Анатольевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>зав. кожно-венерологическим отд-нием, врач высшей квалификационной категории</p></bio><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zalevskaya</surname><given-names>O V</given-names></name><name xml:lang="ru"><surname>Залевская</surname><given-names>Ольга Владимировна</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., врач-дерматовенеролог</p></bio><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Chernysheva</surname><given-names>N V</given-names></name><name xml:lang="ru"><surname>Чернышёва</surname><given-names>Нина Васильевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-дерматовенеролог высшей категории</p></bio><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zhukovsky</surname><given-names>R O</given-names></name><name xml:lang="ru"><surname>Жуковский</surname><given-names>Ростислав Олегович</given-names></name></name-alternatives><bio xml:lang="ru"><p>зав. центральным отд. специализированной помощи, врач-дерматовенеролог</p></bio><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Moscow Regional Clinical Skin and Venereal Dispensary Ministry of Health of Moscow Region</institution></aff><aff><institution xml:lang="ru">ГБУЗ МО «Московский областной клинический кожно-венерологический диспансер» Минздрава Московской области</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Moscow Scientific and Practical Center of Dermatovenerology and Cosmetology</institution></aff><aff><institution xml:lang="ru">ГБУЗ г. Москвы «Московский научно-практический центр дерматовенерологии и косметологии Департамента здравоохранения г. Москвы»</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Central District Hospital of Stupino</institution></aff><aff><institution xml:lang="ru">ГБУЗ МО «Ступинская центральная районная клиническая больница»</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">Moscow Regional Clinical Skin and Venereal Dispensary, Ministry of Health of Moscow Region</institution></aff><aff><institution xml:lang="ru">ГБУЗ МО «Московский областной клинический кожно-венерологический диспансер» Минздрава Московской области</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2018-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2018</year></pub-date><volume>90</volume><issue>4</issue><issue-title xml:lang="en">VOL 90, NO4 (2018)</issue-title><issue-title xml:lang="ru">ТОМ 90, №4 (2018)</issue-title><fpage>96</fpage><lpage>99</lpage><history><date date-type="received" iso-8601-date="2020-04-10"><day>10</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2018, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2018, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/32506">https://ter-arkhiv.ru/0040-3660/article/view/32506</self-uri><abstract xml:lang="en"><p>The article presents literature data for the last 10 years on specific liver damage. There are three own clinical cases of syphilitic hepatitis, one of them - with a lethal outcome. Attention is drawn to the importance of early diagnosis of syphilitic hepatitis. The main criteria for the diagnosis of this pathology.</p></abstract><trans-abstract xml:lang="ru"><p>В статье представлены данные литературы, посвященные специфическим поражениям печени, за последние 10 лет. Описаны три собственных клинических наблюдения сифилитического гепатита, один из случаев - с летальным исходом. Обращено внимание на важность ранней диагностики сифилитического гепатита. Изложены основные критерии диагностики этой патологии.</p></trans-abstract><kwd-group xml:lang="en"><kwd>visceral syphilis</kwd><kwd>syphilitic hepatitis</kwd><kwd>late forms of syphilis</kwd><kwd>diagnosis of syphilitic hepatitis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>висцеральный сифилис</kwd><kwd>сифилитический гепатит</kwd><kwd>поздние формы сифилиса</kwd><kwd>диагностика сифилитического гепатита</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Yoshikawa K, Aida Y, Seki N, Miyazaki T, Itagaki M, Ishiguro H, Abe H, Sutoh S, Sakata A, Aizawa Y. Early syphilitic hepatitis concomitant with nephrotic syndrome followed by acute kidney injury. Clin J Gastroenterol. 2014 Aug;7(4):349-54. doi: 10.1007/s12328-014-0499-x</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Mulder C.J, Cho R.S, Harrison S.A, Cebe K, Francis J.M. Syphilitic hepatitis uncommon presentation of an old scourge. 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