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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">32359</article-id><article-id pub-id-type="doi">10.17116/terarkh20178911105-110</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Editorial article</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Передовая статья</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Evolution of laboratory markers for systemic bacterial infections</article-title><trans-title-group xml:lang="ru"><trans-title>Эволюция лабораторных маркеров системных бактериальных инфекций</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ryabkova</surname><given-names>N L</given-names></name><name xml:lang="ru"><surname>Рябкова</surname><given-names>Н Л</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vezikova</surname><given-names>N N</given-names></name><name xml:lang="ru"><surname>Везикова</surname><given-names>Н Н</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Петрозаводский государственный университет»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-11-15" publication-format="electronic"><day>15</day><month>11</month><year>2017</year></pub-date><volume>89</volume><issue>11</issue><issue-title xml:lang="en">VOL 89, NO11 (2017)</issue-title><issue-title xml:lang="ru">ТОМ 89, №11 (2017)</issue-title><fpage>105</fpage><lpage>110</lpage><history><date date-type="received" iso-8601-date="2020-04-10"><day>10</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/32359">https://ter-arkhiv.ru/0040-3660/article/view/32359</self-uri><abstract xml:lang="en"><p>The paper reviews the data available in the literature on existing laboratory markers for systemic bacterial infection, among which C-reactive protein, proinflammatory cytokines, procalcitonin test, and presepsin receive primary emphasis.</p></abstract><trans-abstract xml:lang="ru"><p>Аннотация Представлен обзор литературы по существующим лабораторным маркерам системной бактериальной инфекции, среди которых основное внимание уделяется С-реактивному белку, провоспалительным цитокинам, прокальцитониновому тесту и пресепсину.</p></trans-abstract><kwd-group xml:lang="en"><kwd>marker for bacterial infection</kwd><kwd>sepsis</kwd><kwd>C-reactive protein</kwd><kwd>procalcitonin</kwd><kwd>presepsin</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>маркер бактериальной инфекции</kwd><kwd>сепсис</kwd><kwd>С-реактивный белок</kwd><kwd>прокальцитонин</kwd><kwd>пресепсин</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb S, Beale RJ, Vincent JL, Moreno R. 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