Terapevticheskii arkhivTerapevticheskii arkhivТерапевтический архив0040-36602309-5342LLC Obyedinennaya Redaktsiya3212610.17116/terarkh20168812116-119Editorial articleПередовая статьяReview ArticleDepression, anxiety, stress, and mortalityДепрессия, тревога, стресс и смертностьBelialovF IБеляловФ ИИркутская государственная медицинская академия последипломного образования Минздрава России151220168812VOL 88, NO12 (2016)ТОМ 88, №12 (2016)11611910042020Copyright ©; 2016, Consilium MedicumCopyright ©; 2016, ООО "Консилиум Медикум"2016Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc-sa/4.0https://ter-arkhiv.ru/0040-3660/article/view/32126

The analytical paper summarizes the main results of recent investigations of the relationships of depression, anxiety, and stress with overall and cardiovascular mortality. It shows that depression and stress are associated with an increased risk of death mainly from cardiovascular diseases, and depression treatment and stress control can increase life expectancy.

Аннотация В аналитической работе обобщены основные результаты последних исследований связей депрессии, тревоги, стресса с общей и сердечно-сосудистой смертностью. Показано, что депрессия и стресс ассоциируются с возрастанием риска смерти, преимущественно от сердечно-сосудистых заболеваний, а лечение депрессии и контроль стресса могут увеличить продолжительность жизни.

depressionanxietystressmortalitycardiovascular mortalityдепрессиятревогастресссмертностьсердечно-сосудистая смертностьБелялов Ф.И., Погодаева С.В., Зайцев А.П., Свистунов В.В., Семенов А.В. Медицинская демография и причины смертности населения Иркутска. Иркутск: РИО ИГМАПО; 2015.Демографический ежегодник России. 2014: Стат. сб. Росстат. M., 2014. Ссылка активна на 01.12.2015. Доступно по: http://www.gks.ru/wps/wcm/conect/rosstat_main/rosstat/ru/statistics/publications/catalog/doc_1137674209312Walker E, McGee RE, Druss BG. Mortality in Mental Disorders and Global Disease Burden Implications:A Systematic Review and Meta-analysis. JAMA Psychiatry. 2015;72(4):334-341. doi:10.1001/jamapsychiatry.2014.2502Kitzlerova E, Anders M. The role of some new factors in the pathophysiology of depression and cardiovascular disease:overview of recent research. Neuro Endocrinol Lett. 2007;28(6):832-840.Barton DA, Dawood T, Lambert EA, et al. Sympathetic activity in major depressive disorder:identifying those at increased cardiac risk? J Hypertens. 2007;25(10):2117-2124. doi:10.1097/HJH.0b013e32829baae7Kop WJ, Stein PK, Tracy RP, et al. Autonomic Nervous System Dysfunction and Inflammation Contribute to the Increased Cardiovascular Mortality Risk Associated With Depression. Psychosom Med. 2010;72(7):626-635. doi:10.1097/PSY.0b013e3181eadd2bvon Kanel R. Acute mental stress and hemostasis:When physiology becomes vascular harm. Thromb Res. 2015;135, Suppl 1:S52-55. doi:10.1016/S0049-3848(15)50444-1Austin AW, Wissmann T, von Kanel R. Stress and hemostasis:an update. SeminThrombHemost. 2013;39(8):902-912. doi:10.1055/s-0033-1357487Погосова Г.В. Депрессия — фактор риска развития ишемической болезни сердца и предиктор коронарной смерти: 10 лет научного поиска. Кардиология. 2011;2:59-66.Emily AK, James AF, Bush DE, et al. Relation of Anxiety and Adherence to Risk-Reducing Recommendations Following Myocardial Infarction. The American Journal of Cardiology. 2009;103[12]:1629-1634. doi:10.1016/j.amjcard.2009.02.014Murphy BM, Grande MR, Navaratnam HS, et al. Are poor health behaviours in anxious and depressed cardiac patients explained by sociodemographic factors? Eur J Prev Cardiol. 2013;20(6):995-1003. doi:10.1177/2047487312449593Tomenson B, McBeth J, Chew-Graham CA, et al. Somatization and Health Anxiety as Predictors of Health Care Use. Psychosom Med. 2012;74(6):656-664. doi:10.1097/PSY.0b013e31825cb140Dempe C, Junger J, Hoppe S, et al. Association of anxious and depressive symptoms with medication nonadherence in patients with stable coronary artery disease. J Psychosom Res. 2013;74(2):122-127. doi:10.1016/j.jpsychores.2012.12.003Bet PM, Penninx BW, van Laer SD, et al. Current and remitted depression and anxiety disorders as risk factors for medication nonadherence. J Clin Psychiatry. 2015;76(9):e1114-1121. doi:10.4088/JCP.14m09001Оганов Р.Г., Погосова Г.В., Колтунов И.Е., Ромасенко Л.В., Деев А.Д., Юферева Ю.М. Депрессивная симптоматика ухудшает прогноз сердечно-сосудистых заболеваний и снижает продолжительность жизни больных артериальной гипертонией и ишемической болезнью сердца. Кардиология. 2012;12:59-66.Gump BB, Matthews KA, Eberly LE et al. Depressive symptoms and mortality in men:results from the Multiple Risk Factor Intervention Trial. Stroke. 2005;36(1):98-102. doi:10.1161/01.STR.0000149626.50127.d0Markkula N, Harkanen T, Perala J, et al. Mortality in people with depressive, anxiety and alcohol use disorders in Finland. Br J Psychiatry. 2012;200(2):143-149. doi:10.1192/bjp.bp.111.094904Lasserre AM, Marti-Soler H, Strippoli MP, et al. Clinical and course characteristics of depression and all-cause mortality:A prospective population-based study. J Affect Disord. 2016;189:17-24. doi:10.1016/j.jad.2015.09.010Bogner HR, Morales KH, Reynolds CF 3rd, et al. Course of depression and mortality among older primary care patients. Am J Geriatr Psychiatry. 2012;20(10):895-903. doi:10.1097/JGP.0b013e3182331104Zhang JP, Kahana B, Kahana E, et al. Joint Modeling of Longitudinal Changes in Depressive Symptoms and Mortality in a Sample of Community-Dwelling Elderly People. Psychosom Med. 2009;71(7):704-714. doi:10.1097/PSY.0b013e3181ac9bceAlmeida OP, Alfonso H, Hankey GJ, Flicker L. Depression, Antidepressant Use and Mortality in Later Life: The Health in Men Study. PLoS ONE. 2010;5(6):e11266. doi:10.1371/journal.pone.0011266Cuijpers P, Vogelzangs N, Twisk J, et al. Differential mortality rates in major and subthreshold depression:meta-analysis of studies that measured both. Br J Psychiatry. 2013;202(1):22-27. doi:10.1192/bjp.bp.112.112169Houle JN. Depressive Symptoms and All-Cause Mortality in a Nationally Representative Longitudinal Study With Time-Varying Covariates. Psychosom Med. 2013;75(3):297-304. doi:10.1097/PSY.0b013e31828b37beGallo JJ, Hwang S, Joo JH, et al. Multimorbidity, Depression, and Mortality in Primary Care:Randomized Clinical Trial of an Evidence-Based Depression Care Management Program on Mortality Risk. J Gen Intern Med. J Gen Intern Med. 2016;31(4):380-386. doi:10.1007/s11606-015-3524-ySurtees PG, Wainwright NWJ, Luben RN et al. Depression and Ischemic Heart Disease Mortality: Evidence From the EPIC-Norfolk United Kingdom Prospective Cohort Study. Am J Psychiatry 2008;165:515-523. doi:10.1176/appi.ajp.2007.07061018Whang W, Kubzansky LD, Kawachi I, et al. Depression and Risk of Sudden Cardiac Death and Coronary Heart Disease in Women:Results From the Nurses’ Health Study. J Am Coll Cardiol 2009;53(11):950-958. doi:10.1016/j.jacc.2008.10.060Lee PL. Depressive symptoms negate the beneficial effects of physical activity on mortality risk. Int J Aging Hum Dev. 2013;76(2):165-179.Gallo JJ, Bogner HR, Morales KH, et al. The Effect of a Primary Care Practice-Based Depression Intervention on Mortality in Older Adults:A Randomized Trial. Ann Intern Med. 2007;146:689-698.Gallo JJ, Morales KH, Bogner HR, et al. Long term effect of depression care management on mortality in older adults:follow-up of cluster randomized clinical trial in primary care. BMJ. 2013;346:f2570. doi:10.1136/bmj.f2570.Stewart JC, Perkins AJ, Callahan CM. Effect of Collaborative Care for Depression on Risk of Cardiovascular Events:Data From the IMPACT Randomized Controlled Trial. Psychosomatic Medicine. 2014;76(1):29-37. doi:10.1097/PSY.0000000000000022Saeed Mirza S, Arfan Ikram M, Hofman A, Tiemeier H. Anxiety does not predict mortality. A population-based study. World Psychiatry. 2015;14(1):103-104. doi:10.1002/wps.20192Mykletun A, Bjerkeset O, Overland S, et al. Levels of anxiety and depression as predictors of mortality:the HUNT study. Br J Psychiatry. 2009;195(2):118-125. doi:10.1192/bjp.bp.108.054866Phillips AC, Batty GD, Gale CR, et al. Generalized Anxiety Disorder, Major Depressive Disorder, and Their Comorbidity as Predictors of All-Cause and Cardiovascular Mortality:The Vietnam Experience Study. Psychosom Med. 2009;71(4):395-403. doi:10.1097/PSY.0b013e31819e6706Phillips AC. Generalised Anxiety Disorder, Mortality and Disease:A Stronger Predictor than Major Depressive Disorder. In: Anxiety and Related Disorders. Edited by: Ágnes Szirmai. 2011.Celano CM, Millstein RA, Bedoya CA, et al. Association between anxiety and mortality in patients with coronary artery disease: A meta-analysis. Am Heart J. 2015;170(6):1105-1115. doi:10.1016/j.ahj.2015.09.013Meyer T, Buss U, Herrmann-Lingen C. Role of Cardiac Disease Severity in the Predictive Value of Anxiety for All-Cause Mortality. Psychosom Med. 2010;72(1):9-15. doi:10.1097/PSY.0b013e3181c64fc0Kim HK, Park JH, Park JH, et al. Differences in Adherence to Antihypertensive Medication Regimens According to Psychiatric Diagnosis:Results of a Korean Population-Based Study. Psychosom Med. 2010;72(1):80-87. doi:10.1097/PSY.0b013e3181c4e3e9Bauer LK, Caro MA, Beach SR, et al. Effects of Depression and Anxiety Improvement on Adherence to Medication and Health Behaviors in Recently Hospitalized Cardiac Patients. The American Journal of Cardiology. 2012;109(10):1266-1271. doi:10.1016/j.amjcard.2011.12.017Watkins LL, Blumenthal JA, Babyak MA, et al. Phobic Anxiety and Increased Risk of Mortality in Coronary Heart Disease. Psychosom Med. 2010;72(7):664-671. doi:10.1097/PSY.0b013e3181e9f357Palmaro A, Dupouy J, Lapeyre-Mestre M. Benzodiazepines and risk of death: Results from two large cohort studies in France and UK. Eur Neuropsychopharmacol. 2015;25(10):1566-1577. Benzodiazepines and risk of death: Results from two large cohort studies in France and UKWeich S, Pearce HL, Croft P, et al. Effect of anxiolytic and hypnotic drug prescriptions on mortality hazards:retrospective cohort study. BMJ. 2014;348:g1996. doi:10.1136/bmj.g1996Belleville G. Mortality hazard associated with anxiolytic and hypnotic drug use in the National Population Health Survey. Can J Psychiatry. 2010;55(9):558-567.Marra EM, Mazer-Amirshahi M, Brooks G, et al. Benzodiazepine Prescribing in Older Adults in U.S. Ambulatory Clinics and Emergency Departments (2001-10). J Am Geriatr Soc. 2015;63(10):2074-2081. doi:10.1111/jgs.13666Roelfs D, Shor E, Davidson K, Schwartz J. War-related stress exposure and mortality:a meta-analysis. Int J Epidemiol. 2010;39(6):1499-509. doi:10.1093/ije/dyq132Nielsen RN, Kristensen TS, Schnohr P, Gronbk M. Perceived Stress and Cause-specific Mortality Among men and Women:Results From a Prospective Cohort Study. Am J Epidemiol. 2008;168(5):481-491. doi:10.1093/aje/kwn157Roelfs DJ, Shor E, Davidson KW, Schwartz JE. Losing Life and Livelihood:A Systematic Review and Meta-Analysis of Unemployment and All-Cause Mortality. Social science & medicine (1982). 2011;72(6):840-854. doi:10.1016/j.socscimed.2011.01.005Aldwin CM, Molitor N-T, Avron S, Levenson MR, Molitor J, Igarashi H. Do Stress Trajectories Predict Mortality in Older Men? Longitudinal Findings from the VA Normative Aging Study. Journal of Aging Research. 2011;2011:896109. doi:10.4061/2011/896109Razvodovsky YE. Psychosocial distress as a risk factor of ischemic heart disease mortality. Psychiatr Danub. 2013;25(1):68-75.Schwartz BG, Pezzullo JC, McDonald SA, et al. How the 2008 Stock Market Crash and Seasons Affect Total and Cardiac Deaths in Los Angeles County. The American Journal of Cardiology. 2012;109(10):1445-1448. doi:10.1016/j.amjcard.2012.01.354Aoki T, Fukumoto Y, Yasuda S, et al. The Great East Japan Earthquake Disaster and cardiovascular diseases. Eur Heart J. 2012;33(22):2796-2803. doi:10.1093/eurheartj/ehs288Robert AK, Scott M, Justin L, et al. Comparison of Total and Cardiovascular Death Rates in the Same City During a Losing Versus Winning Super Bowl Championship. The American Journal of Cardiology. 2009;103[12]:1647-1650. doi:10.1016/j.amjcard.2009.02.012Fang F, Fall K, Mittleman MA, et al. Suicide and Cardiovascular Death after a Cancer Diagnosis. N Engl J Med. 2012;366(14): 1310-1318. doi:10.1056/NEJMoa1110307Linden W, Phillips MJ, Leclerc J. Psychological treatment of cardiac patients:a meta-analysis. Eur Heart J. 2007;28:2972-2984. doi:http://dx.doi.org/10.1093/eurheartj/ehm504