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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">31888</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Editorial article</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Передовая статья</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Enteric microbiocenotic modifiers and ways of enhancing their efficacy</article-title><trans-title-group xml:lang="ru"><trans-title>Корректоры микробиоценоза кишечника и пути повышения их эффективности</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Lipova</surname><given-names>E V</given-names></name><name xml:lang="ru"><surname>Липова</surname><given-names>Е В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Yakovlev</surname><given-names>A B</given-names></name><name xml:lang="ru"><surname>Яковлев</surname><given-names>А Б</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Aivazian</surname><given-names>A A</given-names></name><name xml:lang="ru"><surname>Айвазян</surname><given-names>А А</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">«Центральная государственная медицинская академия» Управления делами Президента РФ</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2015-11-15" publication-format="electronic"><day>15</day><month>11</month><year>2015</year></pub-date><volume>87</volume><issue>11</issue><issue-title xml:lang="en">VOL 87, NO11 (2015)</issue-title><issue-title xml:lang="ru">ТОМ 87, №11 (2015)</issue-title><fpage>139</fpage><lpage>143</lpage><history><date date-type="received" iso-8601-date="2020-04-10"><day>10</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2015, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2015, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/31888">https://ter-arkhiv.ru/0040-3660/article/view/31888</self-uri><abstract xml:lang="en"><p>Efficient recovery of enteric microbiocenosis is one of the central problems not only in gastroenterology, but also in a number of related areas. This problem becomes particularly pressing after antibiotic treatment. The combined modifiers of enteric microbiocenosis are most effective among other symbiotic drugs. Bion-3 apart from symbionts contains a vitamin/mineral complex and acts as an adaptogen.</p></abstract><trans-abstract xml:lang="ru"><p>Проблема эффективного восстановления микробиоценоза кишечника — одна из центральных не только в гастроэнтерологии, но в ряде смежных специальностей. Особенно остро эта проблема возникает после лечения антибактериальными препаратами. Комбинированные корректоры микробиоценоза кишечника — наиболее эффективные среди всех симбиотических препаратов. Бион-3, кроме симбионтов, содержит витаминно-минеральный комплекс и выполняет функцию адаптогена.</p></trans-abstract><kwd-group xml:lang="en"><kwd>probiotics</kwd><kwd>prebiotics</kwd><kwd>symbiotics</kwd><kwd>enteric microbiocenosis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>пробиотики</kwd><kwd>пребиотики</kwd><kwd>симбиотики</kwd><kwd>микробиоценоз кишечника</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Грин Н., Стаут У., Тейлор Д. Биология. М.: МИР; 1990.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Современная микробиология. Прокариоты: в 2-х т. Пер. с англ. Под ред. Й. Ленглера, Г. Древса, Г. Шлегеля. М.: МИР; 2005.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Бондаренко В.М., Грачева Н.М., Мацулевич Т.В., Воробьев А.А.. Микроэкологические изменения кишечника и их коррекция с помощью лечебно-профилактических препаратов. URL: http://www.gastroportal.ru/php/content.php?id=1344</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>McGuire MK, McGuire MA. Human milk: mother nature’s prototypical probiotic food? Advances in nutrition. 2015;6(1):112-123. doi: 10.3945/an.114.007435.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Богомолова Н. Микроорганизмы вышли из тени. Газета «Поликлиника №1 на Сивцевом Вражке». 2015;16:1-5.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Issa I, Moucari R. Probiotics for antibiotic-associated diarrhea: do we have a verdict? World J Gastroenterol. 2014;20(47):17788-17795. doi: 10.3748/wjg.v20.i47.17788.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Nami Y, Haghshenas B, Abdullah N, Barzegari A. et al. Probiotics or antibiotics: future challenges in medicine. J Med Microbiol. 2015;64(Pt 2):137-146. doi: 10.1099/jmm.0.078923-0.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Recine N, Palma E, Domenici L, Giorgini M, Imperiale L. et al. Restoring vaginal microbiota: biological control of bacterial vaginosis. A prospective case-control study using Lactobacillus rhamnosus BMX 54 as adjuvant treatment against bacterial vaginosis. Arch Gynecol Obstet. 2015 Jul 5. Online resource: http://www.ncbi.nlm.nih.gov/pubmed/?term=Recine+N%2C+Palma+E%2C+Domenici+L%2C+Giorgini+M%2C+Imperiale+L.+et+al.+Restor-ing+vaginal+microbiota%3A+biological+control+of+bacterial+vaginosis.+A+pro-spective+case-control+study+using+Lactobacillus+rhamnosus+BMX+54+as+adjuvant+treatment+against+bacterial+vaginosis</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Shoaib A, Dachang W, Xin Y. Determining the role of a probiotic in the restoration of intestinal microbial balance by molecular and cultural techniques. Genet Mol Res. 2015;14(1):1526-1637. doi: 10.4238/2015.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Esposito S, Umbrello G, Castellazzi L, Principi N. Treatment of Clostridium difficile infection in pediatric patients. Expert Rev Gastroenterol Hepatol. 2015;9(6):747-755. doi: 10.1586/17474124.2015.1039988.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Na JY, Park JM, Lee KS, Kang JO. et al. Clinical Characteristics of Symptomatic Clostridium difficile Infection in Children: Conditions as Infection Risks and Whether Probiotics Is Effective. Pediatr gastroenterol, hepatol nutrit. 2014;17(4):232-238. doi: 10.5223/pghn.2014.17.4.232.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Sawas T, Al Halabi S, Hernaez R, Carey WD, Cho WK. Patients Receiving Prebiotics and Probiotics Before Liver Transplantation Develop Fewer Infections Than Controls: A Systematic Review and Meta-analysis. Clinical gastroenterology and hepatology: the official clinical practice. J Am Gastroenterol Assoc. 2015;pii:S1542-3565(15)00762-4. doi: 10.1016/j.cgh.2015.05.027.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Téllez G, Lauková A, Latorre JD, Hernandez-Velasco X. et al. Food-producing animals and their health in relation to human health. Microbial Ecol Health Dis. 2015;(26):258-276. doi: 10.3402/mehd.v26.25876.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Ливзан М.А. Бактериальный вагиноз: место пероральной пробиотической терапии. Лечащий врач. 2009;2:52-55.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Baquerizo Nole KL, Yim E, Keri JE. Probiotics and prebiotics in dermatology. J Am Academ Dermatol. 2014;71(4):814-821. doi: 10.1016/j.jaad.2014.04.050.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Липова Е.В. Дискуссионные вопросы бактериального вагиноза: взгляд дерматовенеролога. Доктор.Ру. Гинекология. Эндокринология. 2015;1(102):30-34.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Pérez C. Probiotics for the treating acute diarrhea and preventing antibiotic-associated diarrhea in children. Nutriciónhospitalaria. 2015;31:Suppl. 1:64-67. doi: 10.3305/nh.2015.31.sup1.8709.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Goldstein EJ, Tyrrell KL, Citron DM. Lactobacillus species: taxonomic complexity and controversial susceptibilities. Clin Infect Dis. 2015;60 Suppl 2:S98-107. doi: 10.1093/cid/civ072.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Khalighi AR, Khalighi MR, Behdani R, Jamali J, Khosravi A. et al. Evaluating the efficacy of probiotic on treatment in patients with small intestinal bacterial overgrowth (SIBO) — a pilot study. Indian J Med Res. 2014;140(5):604-608.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Xie C, Li J, Wang K, Li Q, Chen D. Probiotics for the prevention of antibiotic-associated diarrhoea in older patients: a systematic review. Travel Med Infect Dis. 2015;13(2):128-134. doi: 10.1016/j.tmaid.2015.03.001.</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Руководство по медицинской микробиологии. Частная медицинская микробиология и этиологическая диагностика инфекций. Книга II. Под ред. А.С. Лабинской, Н.Н. Костюковой, С.М. Ивановой. М.: БИНОМ; 2010.</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Бион 3. Инструкция к применению. URL: http://instrukciya-otzyvy.ru/962-bion-3-po-primeneniyu-analogi-tabletki-vitaminov-zhevatelnye-kid-aktiveyt-sostav.html.</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Drago L, De Vecchi E, Toscano M, Vassena C et al. Treatment of atopic dermatitis eczema with a high concentration of Lactobacillus salivarius LS01 associated with an innovative gelling complex: a pilot study on adults. J Clin Gastroenterol. 2014;48 Suppl 1:S47-51. doi: 10.1097/mcg.0000000000000249.</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>Al-Ghazzewi FH, Tester RF. Impact of prebiotics and probiotics on skin health. Beneficial Microbes. 2014;5(2):99-107. doi: 10.3920/bm2013.0040.</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>Bertelsen RJ, Brantsæter AL, Magnus MC, Haugen M, Myhre R. et al. Probiotic milk consumption in pregnancy and infancy and subsequent childhood allergic diseases. J Allergy Clin Immunol. 2014;133(1):165-171.e1-8. doi: 10.1016/j.jaci.2013.07.032.</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>Снарская Е.С. Лактофильтрум в терапии атопического дерматита. Современные проблемы дерматовенерологии. 2011;2(15): 19-22.</mixed-citation></ref></ref-list></back></article>
