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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="editorial" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">31519</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Editorial article</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Передовая статья</subject></subj-group><subj-group subj-group-type="article-type"><subject>Editorial</subject></subj-group></article-categories><title-group><article-title xml:lang="en">New approaches to diagnosing and treating Crohn's disease</article-title><trans-title-group xml:lang="ru"><trans-title>Новые подходы к диагностике и лечению болезни Крона</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Maev</surname><given-names>I V</given-names></name><name xml:lang="ru"><surname>Маев</surname><given-names>И В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Andreev</surname><given-names>D N</given-names></name><name xml:lang="ru"><surname>Андреев</surname><given-names>Д Н</given-names></name></name-alternatives><email>dna-mit8@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО "Московский государственный медико-стоматологический университет им. А.И. Евдокимова" Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2014-08-15" publication-format="electronic"><day>15</day><month>08</month><year>2014</year></pub-date><volume>86</volume><issue>8</issue><issue-title xml:lang="en">VOL 86, NO8 ()</issue-title><issue-title xml:lang="ru">ТОМ 86, №8 (2014)</issue-title><fpage>4</fpage><lpage>12</lpage><history><date date-type="received" iso-8601-date="2020-04-10"><day>10</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2014, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2014, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/31519">https://ter-arkhiv.ru/0040-3660/article/view/31519</self-uri><abstract xml:lang="en"><p>The paper presents current views on the diagnosis and medical treatment of Crohn's disease (CD). It considers the present-day principles in the classification, evaluation of the severity of the disease, and its diagnostic criteria. There are actual medical treatment regimens for CD, regulated by the project of Russian clinical guidelines for the diagnosis and treatment of CD in adults (2013), which were drawn up by leading Russian experts relying on the European evidence-based consensus on the diagnosis and management of CD (2010). Promising treatment options for CD, which affect the key molecules of the pathogenesis of this disease, are considered.</p></abstract><trans-abstract xml:lang="ru"><p>Аннотация. Представлены современные взгляды на диагностику и консервативное лечение болезни Крона (БК). Рассмотрены современные принципы классификации, оценки тяжести и диагностические критерии рассматриваемого заболевания. Приведены актуальные схемы консервативной терапии БК, регламентированные проектом Российских клинических рекомендаций по диагностике и лечению БК у взрослых (2013), составленных ведущими отечественными экспертами на основании Европейского доказательного консенсуса по диагностике и лечению БК (2010). Рассмотрены перспективные методы лечения больных БК, влияющие на ключевые молекулы патогенеза данного заболевания.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Crohn's disease</kwd><kwd>diagnosis</kwd><kwd>treatment</kwd><kwd>guidelines</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>болезнь Крона</kwd><kwd>диагностика</kwd><kwd>лечение</kwd><kwd>рекомендации</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Парфенов А.И. Болезнь Крона: к 80-летию описания. Тер арх. 2013; 8: 35-42.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Sands B.E., Siegel C.A. Crohn's disease. 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