Terapevticheskii arkhivTerapevticheskii arkhivТерапевтический архив0040-36602309-5342LLC Obyedinennaya Redaktsiya31466Editorial articleПередовая статьяReview ArticleEvolution of clinical ideas about Zollinger-Ellison syndromeЭволюция клинических представлений о синдроме Золлингера-ЭллисонаMaevI VМаевИ ВAndreevD NАндреевД Нdna-mit8@mail.ruKucheriavyĭIu AКучерявыйЮ АBarkalovaE VБаркаловаЕ ВМосковский государственный медико-стоматологический университет им. А.И. Евдокимова Минздрава России15022014862VOL 86, NO2 ()ТОМ 86, №2 (2014)828910042020Copyright ©; 2014, Consilium MedicumCopyright ©; 2014, ООО "Консилиум Медикум"2014Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc-sa/4.0https://ter-arkhiv.ru/0040-3660/article/view/31466

The paper gives the current views of the diagnosis and treatment of Zollinger-Ellison syndrome (ZES). It underlines the importance of including ZES in differential diagnosis in patient with frequently recurrent and standard-dose proton pump inhibitor therapy-resistant erosive and ulcerative lesions of the upper gastrointestinal tract. It provides the current stepwise algorithm for the diagnosis of the pathology in question. Relevant and promising treatments in patients with ZES are considered.

Аннотация. Представлены современные взгляды на диагностику и лечение синдрома Золлингера-Эллисона (СЗЭ). Подчеркивается важность включения СЗЭ в круг дифференциальной диагностики у пациентов с часто рецидивирующими и резистентными к терапии стандартными дозами ингибиторов протонного насоса эрозивно-язвенными поражениями верхних отделов желудочно-кишечного тракта. Представлен современный поэтапный алгоритм диагностики обсуждаемой патологии. Рассмотрены актуальные и перспективные методы лечения больных с СЗЭ.

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