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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">31223</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Editorial article</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Передовая статья</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Difficulties and errors in the management tactics of patients with chronic pancreatitis</article-title><trans-title-group xml:lang="ru"><trans-title>Трудности и ошибки в тактике ведения больных хроническим панкреатитом</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Maev</surname><given-names>I V</given-names></name><name xml:lang="ru"><surname>Маев</surname><given-names>И В</given-names></name></name-alternatives><email>proped@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kucheriavyĭ</surname><given-names>Iu A</given-names></name><name xml:lang="ru"><surname>Кучерявый</surname><given-names>Ю А</given-names></name></name-alternatives><email>proped@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Samsonov</surname><given-names>A A</given-names></name><name xml:lang="ru"><surname>Самсонов</surname><given-names>А А</given-names></name></name-alternatives><email>aleksey.samsonov@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Andreev</surname><given-names>D N</given-names></name><name xml:lang="ru"><surname>Андреев</surname><given-names>Д Н</given-names></name></name-alternatives><email>dna-mit8@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО "Московский государственный медико-стоматологический университет им. А.И. Евдокимова" Минздрава РФ</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-02-15" publication-format="electronic"><day>15</day><month>02</month><year>2013</year></pub-date><volume>85</volume><issue>2</issue><issue-title xml:lang="en">VOL 85, NO2 ()</issue-title><issue-title xml:lang="ru">ТОМ 85, №2 (2013)</issue-title><fpage>65</fpage><lpage>72</lpage><history><date date-type="received" iso-8601-date="2020-04-10"><day>10</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/31223">https://ter-arkhiv.ru/0040-3660/article/view/31223</self-uri><abstract xml:lang="en"><p>The paper deals with the difficulties and errors that are most commonly used in clinical practice to manage patients with chronic pancreatitis (CP). The higher interest in CP is inspired by the wide prevalence of this disease with its constant upward trend. At the same time, a variety of the etiological forms of CP, from generically determined to infectious and autoimmune ones, in combination with a weak theoretical basis in a number of practitioners gives rise to a broad spectrum of tactical errors in the management of patients with CP. The paper summarizes and analyzes the most common defects and errors in the management tactics of patients with this nosological entity, including the aspects of diagnosis and medical treatment. Ways to solve the set optimization problems in management protocols for patients with CP are proposed in the context of evidence-based medicine.</p></abstract><trans-abstract xml:lang="ru"><p>Аннотация. Статья посвящена наиболее часто встречающимся в клинической практике трудностям и ошибкам ведения пациентов с хроническим панкреатитом (ХП). Повышенный интерес к проблеме ХП продиктован широкой распространенностью данного заболевания с постоянной тенденцией к росту. При этом многообразие этиологических форм ХП от генетически обусловленных до инфекционных и аутоиммунных в сочетании со слабой теоретической базой у ряда практикующих врачей порождают широкий спектр тактических ошибок в ведении больных ХП. В статье суммированы и проанализированы наиболее распространенные погрешности и ошибки в тактике ведения пациентов с данной нозологической единицей, включая аспекты диагностики и консервативного лечения. Предложены пути к разрешению поставленных вопросов в рамках оптимизации протоколов ведения больных ХП с позиций доказательной медицины.</p></trans-abstract><kwd-group xml:lang="en"><kwd>chronic pancreatitis</kwd><kwd>diagnosis</kwd><kwd>medical treatment</kwd><kwd>pancreatin</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>хронический панкреатит</kwd><kwd>диагностика</kwd><kwd>консервативное лечение</kwd><kwd>панкреатин</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Schneider A., Löhr J.M., Singer M.V. The M-ANNHEIM classification of chronic pancreatitis: introduction of a unifying classification system based on a review of previous classifications of the disease. J Gastroenterol 2007; 42 (2): 101-119.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Chari S.T., Smyrk T.C., Levy M.J. et al. Diagnosis of autoimmune pancreatitis: the Mayo Clinic experience. Clin Gastroenterol Hepatol 2006; 4: 1010-1016.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Маев И.В., Кучерявый Ю.А. Заместительная ферментная терапия при панкреатической недостаточности. Клин персп гастроэнтерол, гепатол 2005; 5: 19-28.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Ihse I., Lilja P., Lundquist I. Feedback regulation of pancreatic enzyme secretion by intestinal trypsin in man. Digestion 1977; 15: 303.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Calan J., Bojarski J.C., Spriner C.J. Raw soya-bean flour increases cholecystokinin release in man. Br J Nutr 1987; 58: 175.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Liener J.E., Goodale R.L., Deshmukh A. et al. Effect of a trypsin inhibitor from soya-beans (Bowman-Birk) on the secretory activity of the human pancreas. Gastroenterology 1988; 94: 419.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Owyang C., Louie D., Tatum D. Feedback regulation of pancreatic enzyme secretion. J Clin Invest 1986; 77: 2042.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Slaff J.I., Jacobson D., Tillman C.R. et al. Protease-specific suppression of pancreatic exocrine secretion. Gastroenterology 1984; 87: 44.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Isakson G., Ihse I. Pain reduction by an oral pancreatic enzyme preparation in chronic pancreatitis. Dig Dis Sci 1983; 28: 97-102.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Белоусова Е.А., Никитина Н.В., Цодиков Г.В. Оптимизация схем лечения хронического панкреатита ферментными препаратами. Фарматека 2008; 13: 103-108.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Ивашкин В.Т., Охлобыстин А.В., Баярмаа Н. Эффективность микрокапсулированных ферментов, покрытых энтеросолюбильной оболочкой, при хроническом панкреатите. Клин перспект гастроэнтерол, гепатол 2001; 5: 15-19.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Weiner K., Graham L.S., Reedy T. et al. Simultaneous gastric emptying of two solid foods. Gastroenterology 1981; 81: 257.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Schuster M.M., Crowell M.D., Koch K.L. Gastrointestinal motility in Health and Disease (2d ed.). London: ВС Decker Inc. Hamilton. 2002; 472.</mixed-citation></ref></ref-list></back></article>
