Terapevticheskii arkhivTerapevticheskii arkhiv0040-36602309-5342LLC Obyedinennaya Redaktsiya31191Research ArticleElectrocardiographic predictors of in-hospital outcomes of acute coronary syndromeProvotorovV M-ShevchenkoI Iqvi63@box.vsi.ru15012013851374110042020Copyright © 2013, Consilium Medicum2013AIM: To estimate the time course of changes in basic electrocardiographic (ECG) parameters in patients with acute coronary syndrome (ACS) as possible predictors of in-hospital outcomes. Materials and methods. The data of 277 patients with acute coronary syndrome (ACS) were used; QT-interval duration was studied by means of an EC12C-01 cardioanalyzer; ST-segment deviation (ΣST), elevation (ΣST-E), and depression (ΣST-D) sums, and corrected QT-interval dispersion (DQTc) were calculated/RESULTS: There were highly significant differences of ΣST in all the patients groups at admission and differences of DQTc in ACS patients with and without ST-segment elevation. The survival rates were significantly different depending on the value of ECG parameters, such as ΣST, ΣST-D, and DQTc/CONCLUSION: The cardioanalyzer can automatically improve the estimation of in-hospital ECG changes and to determine predictors of an ACS outcome.EC12C-01 electrocardioanalyzerST-segment deviation sumcorrected QT-interval dispersionэлектрокардиоанализатор ЭК12К-01сумма отклонения сегмента STкорригированная дисперсия интервала QT[Мравян С.Р., Федорова С.И. ЭКГ-феномен подъема сегмента ST, его причины и клиническое значение. Клин мед 2006; 5: 12-18.][Langer A., Krucoff M.W., Klootwijk P. et al. Prognostic significance of ST segment shift early after resolution of ST elevation in patients with myocardial infarction treated with thrombolytic therapy: the GUSTO-I ST Segment Monitoring Substudy. J Am Coll Cardiol 1998; 31: 783-789.][Тепляков А.Т., Камаев Д.Ю., Калюжин В.В. и др. Прогностическое значение дисперсии интервала QT электрокардиограммы у больных инфарктом миокарда. Бюл Сиб мед 2006; 1: 91-96.][Kligfield P., Gettes L.S., Bailey J.J. et al. AHA/ACC/HRS SCIENTIFIC STATEMENT Recommendations for the Standardization and Interpretation of the Electrocardiogram Part I: The Electrocardiogram and Its Technology A Scientific Statement From the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society Endorsed by the International Society for Computerized Electrocardiology. J Am Coll Cardiol 2007; 49: 1109-1127.][Ипатов П.В., Овсянников В.В., Кутепов Ю.С. Изменения ЭКГ при внутригоспитальном инфаркте миокарда. Военно-мед журн 2006; 5: 65-66.][Atar S., Birnbaum Y. Ischemia-induced ST-segment elevation: classification, prognosis, and therapy. J Electrocardiol 2005; 38 (4 Suppl): 1-7.][Sanchis J., Bodí V., Núñez J. et al. New risk score for patients with acute chest pain, non-ST-segment deviation, and normal troponin concentrations: a comparison with the TIMI risk score. J Am Coll Cardiol 2005; 46 (3): 443-449.][The GRACE Investigators. Rationale and design of the GRACE (Global Registry of Acute Coronary Events) Project: a multinational registry of patients hospitalized with acute coronary syndromes. Am Heart J 2001; 141: 190-199.][de Araújo Gonçalves P., Ferreira J., Aguiar C. et al. TIMI, PURSUIT, and GRACE risk scores: sustained prognostic value and interaction with revascularization in NSTE-ACS. Eur Heart J 2005; 26 (9): 865-872.][Wagner G.S., Macfarlane P., Wellens H. et al. AHA/ACCF/HRS EXPERT CONSENSUS DOCUMENT AHA/ACCF/HRS Recommendations for the Standardization and Interpretation of the Electrocardiogram Part VI: Acute Ischemia/Infarction A Scientific Statement From the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society Endorsed by the International Society for Computerized Electrocardiology. J Am Coll Cardiol 2009; 53: 1003-1011.][Bluzaite I., Brazdzionyte J., Zaliūnas R. et al. QT dispersion and heart rate variability in sudden death risk stratification in patients with ischemic heart disease. Medicine (Kaunas) 2006; 42 (6): 450-454.][Rautaharju P.M., Surawicz B., Gettes L.S. AHA/ACCF/HRS EXPERT CONSENSUS DOCUMENT AHA/ACCF/HRS Recommendations for the Standardization and Interpretation of the Electrocardiogram Part IV: The ST Segment, T and U Waves, and the QT Interval A Scientific Statement From the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society Endorsed by the International Society for Computerized Electrocardiology. J Am Coll Cardiol 2009; 53: 982-991.]