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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">31179</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Editorial article</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Передовая статья</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Interpretation of the concentrations of procalcitonin during infectious and inflammatory processes</article-title><trans-title-group xml:lang="ru"><trans-title>Интерпретация значений концентрации прокальцитонина при инфекционных воспалительных процессах</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Piatnitskiĭ</surname><given-names>I A</given-names></name><name xml:lang="ru"><surname>Пятницкий</surname><given-names>И А</given-names></name></name-alternatives><email>iptg@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sharandak</surname><given-names>A P</given-names></name><name xml:lang="ru"><surname>Шарандак</surname><given-names>А П</given-names></name></name-alternatives><email>sharandak59@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zokina</surname><given-names>T G</given-names></name><name xml:lang="ru"><surname>Зокина</surname><given-names>Т Г</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Berner</surname><given-names>L P</given-names></name><name xml:lang="ru"><surname>Бернер</surname><given-names>Л П</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">Центральная клиническая больница РАН, Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2012-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2012</year></pub-date><volume>84</volume><issue>12</issue><issue-title xml:lang="en">VOL 84, NO12 (2012)</issue-title><issue-title xml:lang="ru">ТОМ 84, №12 (2012)</issue-title><fpage>120</fpage><lpage>124</lpage><history><date date-type="received" iso-8601-date="2020-04-10"><day>10</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2012, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2012, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/31179">https://ter-arkhiv.ru/0040-3660/article/view/31179</self-uri><abstract xml:lang="en"><p>The paper analyzes the most important clinical studies dealing with the measurement of procalcitonin concentrations in patients with lower respiratory tract infections or sepsis. Procalcitonin is a marker of bacterial infection, which is successfully used for diagnosis and antimicrobial therapy monitoring in patients with pneumonia or in septic states. The review presents the latest algorithms for interpreting the concentrations of procalcitonin in clinical practice.</p></abstract><trans-abstract xml:lang="ru"><p>Аннотация. В статье анализируются наиболее значимые в клиническом аспекте исследования, посвященные измерению концентраций прокальцитонина у больных с инфекциями нижних дыхательных путей или сепсисом. Прокальцитонин - маркер бактериальной инфекции, успешно применяемый для диагностики и контроля антимикробной терапии у больных пневмонией или при септических состояниях. В обзоре приводятся последние алгоритмы интерпретации значений концентрации прокальцитонина в клинической практике.</p></trans-abstract><kwd-group xml:lang="en"><kwd>procalcitonin</kwd><kwd>sepsis</kwd><kwd>pneumonia</kwd><kwd>bacterial infectio</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>прокальцитонин</kwd><kwd>сепсис</kwd><kwd>пневмония</kwd><kwd>бактериальная инфекция</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Le Moullec J.M., Jullienne A., Chenais J. et al. The complete sequence of human preprocalcitonin. FEBS Lett 1984; 167 (1): 93-97.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Assicot M., Gendrel D., Carsin H. et al. High serum procalcitonin concentrations in patients with sepsis and infection. Lancet 1993; 341 (8844): 515-518.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Dahaba A.A., Metzler H. Procalcitonin's role in the sepsis cascade. 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