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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">31165</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Editorial article</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Передовая статья</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Melatonin and metabolic syndrome: Is there their association?</article-title><trans-title-group xml:lang="ru"><trans-title>Мелатонин и метаболический синдром: существует ли связь?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Dzherieva</surname><given-names>I S</given-names></name><name xml:lang="ru"><surname>Джериева</surname><given-names>И С</given-names></name></name-alternatives><email>dgerieva@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Volkova</surname><given-names>N I</given-names></name><name xml:lang="ru"><surname>Волкова</surname><given-names>Н И</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Rapoport</surname><given-names>S I</given-names></name><name xml:lang="ru"><surname>Рапопорт</surname><given-names>С И</given-names></name></name-alternatives><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ГОУ ВПО "Ростовский государственный медицинский университет" Минздравсоцразвития России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО "Первый Московский государственный медицинский университет им. И.М. Сеченова" Минздравсоцразвития России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2012-10-15" publication-format="electronic"><day>15</day><month>10</month><year>2012</year></pub-date><volume>84</volume><issue>10</issue><issue-title xml:lang="en">VOL 84, NO10 (2012)</issue-title><issue-title xml:lang="ru">ТОМ 84, №10 (2012)</issue-title><fpage>109</fpage><lpage>112</lpage><history><date date-type="received" iso-8601-date="2020-04-10"><day>10</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2012, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2012, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/31165">https://ter-arkhiv.ru/0040-3660/article/view/31165</self-uri><abstract xml:lang="en"><p>The basis for the current view of the mechanisms for regulating metabolic processes is the hypothesis proposed by the United Kingdom scientists E. Scott and P. Grant that evolutionary fixed adaptation to seasonal environmental changes is impaired. Under the hypothesis, impairment in seasonal and circadian rhythms is the key condition for the occurrence of obesity, arterial hypertension (AH), and type 2 diabetes mellitus. The diseases of civilization, namely obesity, insulin resistance, and AH, are a direct result of chronic metabolic disturbance due to light pollution.</p></abstract><trans-abstract xml:lang="ru"><p>Аннотация. В основе современного взгляда на механизмы регуляции метаболических процессов лежит гипотеза о нарушении эволюционно закрепленной адаптации к сезонным изменениям окружающей среды, предложенная английскими учеными E. Scott и P. Grant. Согласно гипотезе нарушение сезонных и суточных ритмов является основным условием для возникновения ожирения, артериальной гипертонии (АГ) и сахарного диабета 2-го типа. "Болезни цивилизации" - ожирение, инсулинорезистентность и АГ - являются прямым следствием хронического нарушения метаболизма в результате "световой загрязненности".</p></trans-abstract><kwd-group xml:lang="en"><kwd>melatonin</kwd><kwd>circadian rhythms</kwd><kwd>metabolic syndrome</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>мелатонин</kwd><kwd>циркадные ритмы</kwd><kwd>метаболический синдром</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Физиология человека. Руководство в 4 томах. Под ред. R.S. Schidt, G. Thew. Т.1. M: Мир 1985: 232-234.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Lincoln G.A., Richardson M. Photo-neuroendocrine control of seasonal cycles in body weight, pelage growth and reproduction: lessons from the HPD sheep model. 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