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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">31141</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Editorial article</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Передовая статья</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Pulmonary hypertension in rheumatic heart disease: current approaches to diagnosis and therapy</article-title><trans-title-group xml:lang="ru"><trans-title>Легочная гипертония при ревматической болезни сердца: современные подходы к диагностике и терапии</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shostak</surname><given-names>N A</given-names></name><name xml:lang="ru"><surname>Шостак</surname><given-names>Н А</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Klimenko</surname><given-names>A A</given-names></name><name xml:lang="ru"><surname>Клименко</surname><given-names>А А</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Novikov</surname><given-names>I V</given-names></name><name xml:lang="ru"><surname>Новиков</surname><given-names>И В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Demidova</surname><given-names>N A</given-names></name><name xml:lang="ru"><surname>Демидова</surname><given-names>Н А</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Aksenova</surname><given-names>A V</given-names></name><name xml:lang="ru"><surname>Аксенова</surname><given-names>А В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff id="aff1"><institution>ГБОУ ВПО "Российский национальный исследовательский медицинский университет", Москва</institution></aff><pub-date date-type="pub" publication-format="electronic" iso-8601-date="2012-09-15"><day>15</day><month>09</month><year>2012</year></pub-date><pub-date date-type="collection"><year>2012</year></pub-date><volume>84</volume><issue>9</issue><issue-title xml:lang="en">VOL 84, NO9 ()</issue-title><issue-title xml:lang="ru">ТОМ 84, №9 (2012)</issue-title><fpage>89</fpage><lpage>96</lpage><history><date date-type="received" iso-8601-date="2020-04-10"><day>10</day><month>04</month><year>2020</year></date></history><pub-history><event event-type="received"><event-desc>Received:<date date-type="received" iso-8601-date="2020-04-10"><day>10</day><month>04</month><year>2020</year></date></event-desc></event><event event-type="pub"><event-desc>Published:<pub-date date-type="pub" publication-format="electronic" iso-8601-date="2012-09-15"><day>15</day><month>09</month><year>2012</year></pub-date></event-desc></event></pub-history><permissions><copyright-statement xml:lang="en">Copyright ©; 2012, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2012, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/31141">https://ter-arkhiv.ru/0040-3660/article/view/31141</self-uri><abstract xml:lang="en"><p>Pulmonary hypertension is a complex multidisciplinary problem in modern medicine. This review discusses its clinical and pathophysiological type associated with rheumatic heart disease. Current approaches to the pathogenesis and diagnosis of the disease are reflected; basic approaches to its treatment are discussed in terms of current clinical guidelines and new scientific achievements.</p></abstract><trans-abstract xml:lang="ru"><p>Аннотация. В современной медицине легочная гипертония является комплексной мультидисциплинарной проблемой. В настоящем обзоре обсуждается клинико-патофизиологический вариант заболевания, ассоциированный с ревматической болезнью сердца. Отражены современные взгляды на патогенез и диагностику заболевания, приведены основные подходы к лечению с учетом действующих клинических рекомендаций и новых научных достижений.</p></trans-abstract><kwd-group xml:lang="en"><kwd>pulmonary hypertension</kwd><kwd>rheumatic heart disease</kwd><kwd>endothelial dysfunction</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>легочная гипертония</kwd><kwd>ревматическая болезнь сердца</kwd><kwd>дисфункция эндотелия</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>McLaughlin V.V., Archer S.L., Badesch D.B. et al.; ACCF/AHA. ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association. 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