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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">30853</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Editorial article</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Передовая статья</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Systemic lupus erythematosus in men: difficulties of diagnosis and specific features of clinical picture</article-title><trans-title-group xml:lang="ru"><trans-title>Трудности диагностики и особенности клинической картины системной красной волчанки у мужчин</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Klyukvina</surname><given-names>Nataliya Gennad'evna</given-names></name><name xml:lang="ru"><surname>Клюквина</surname><given-names>Наталия Геннадьевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, доц. каф. ревматологии фак. послевузовского профессионального образования врачей Первого МГМУ, тел.: 8-499-614-35-22; Первый Московский государственный медицинский университет</p></bio><email>nataklykvina@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Klyukvina</surname><given-names>N G</given-names></name><bio xml:lang="en"><p>The First State Moscow Medical University</p></bio><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">Первый Московский государственный медицинский университет</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">The First State Moscow Medical University</institution></aff><aff><institution xml:lang="ru"></institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2011-05-15" publication-format="electronic"><day>15</day><month>05</month><year>2011</year></pub-date><volume>83</volume><issue>5</issue><issue-title xml:lang="en">NO5 (2011)</issue-title><issue-title xml:lang="ru">ТОМ 83, №5 (2011)</issue-title><fpage>47</fpage><lpage>50</lpage><history><date date-type="received" iso-8601-date="2020-04-10"><day>10</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2011, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2011, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/30853">https://ter-arkhiv.ru/0040-3660/article/view/30853</self-uri><abstract xml:lang="en"><p>Aim. To characterize specific clinical features of systemic lupus erythematosus (SLE) in male patients.
Material and methods. A total of 146 male patients with verified SLE diagnosis were examined in the Research Institute of Rheumatology.
Results. Literature and original data on SLE clinical characteristics in men were analysed. Diagnostic search and variants of SLE in male patients are described.
Conclusion. To upgrade knowledge on SLE clinical characteristics, further prospective trials should be made.</p></abstract><trans-abstract xml:lang="ru"><p>Цель исследования. Охарактеризовать особенности клинической картины системной красной волчанки (СКВ) у больных мужского пола.
Материалы и методы. Обследовали 146 больных мужского пола с достоверным диагнозом СКВ, наблюдавшихся в НИИР РАМН.
Результаты. Представлен анализ данных литературы и результатов собственных наблюдений относительно особенностей СКВ у мужчин. Показаны диагностический поиск и варианты клинической картины СКВ у больных мужского пола.
Заключение. Для совершенствования знаний об особенностях клинической картины СКВ, в том числе у мужчин, необходимы дальнейшие проспективные наблюдения.</p></trans-abstract><kwd-group xml:lang="en"><kwd>systemic lupus erythematosus</kwd><kwd>male</kwd><kwd>diagnosis</kwd><kwd>SLE variants</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>системная красная волчанка (СКВ)</kwd><kwd>мужской пол</kwd><kwd>диагностика</kwd><kwd>варианты СКВ</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Dubois E. L., Tuffanelli D. L. Clinical manifestations of SLE. Compute analysis of 520 cases. J. A. M. A. 1964; 190: 104-111.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Andrade R. M., Alarcon G. S., Fernandez M. et al. Accelerated damage accrual among men with systemic lupus erythematosus. XLIY. Results from a multiethnic US cohort. Arthr. &amp; Rheum. 2007; 56(2): 622-630.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Kaufman L. D., Gomez-Reino J. J., Heinicke M. H., Gorevic P. D. Male lupus: retrospective analysis of the clinical and laboratory features of 52 patients, with a review of the literature. Semin. Arthr. Rheum. 1989; 18(3): 189-197.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Reveille J. D., Bartolucci A., Alarcon G. S. Prognosis in systemic lupus erythematosus: negative impact of increasing age of onset, black race and thrombocytopenia, as well as causes of death. Arthr. &amp; Rheum. 1990; 33: 37-48.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Wallace D. J., Podell T., Weiner J. et al. Systemic lupus erythematosus survival patterns: experience with 609 patients. J. A. M. A. 1981; 245: 934-938.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Miller M. H., Urowitz M. B., Gladman D. D., Killinger D. W. Systemic lupus erythematosus in males. Medicine (Baltimore) 1983; 62(5): 327-334.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Фоломеев М. Ю., Мирочницкий С. Н., Алекберова З. С. Особенности течения системной красной волчанки у мужчин. Тер. арх. 1981; 7: 30-33.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Фоломеев М. Ю. Системная красная волчанка у мужчин: Автореф. дис. ... канд. мед. наук. М.; 1984.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Sthoeger Z. M., Geltner D., Rider A., Bentwich Z. Systemic lupus erythematosus in 49 Israeli males: a retrospective study. Clin. Exp. Rheumatol. 1987; 5: 233-240.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Ward M. M., Studenski S. Systemic lupus erythematosus in men: multivariate analysis of gender differences in clinical manifestations. J. Rheumatol. 1990; 17(2): 222-224.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Koh W. H., Fong K. Y., Boey M. L., Feng P. H. Systemic lupus erythematosus in 61 oriental males. A study of clinical and laboratory manifestations. Br. J. Rheumatol. 1994; 33(3): 339-342.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Specker C., Becker A., Lakomek H. J. et al. Systemic lupus erythematosus in men - a different prognosis? J. Rheumatol. 1994; 53: 339-345.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Molina J. F., Drencard C., Molina J. et al. Systemic lupus erythematosus in males. A study of 107 Latin American patients. Medicine (Baltimore) 1996; 75: 124-130.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Chang D.-M., Chang C.-C., Kuo S.-Y. et al. The clinical features and prognosis of male lupus in Taiwan. Lupus 1998; 7: 462-468.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Garcia M. A., Marcos J. C., Marcos A. I. et al. Male systemic lupus erythematosus in a Latin-American inception cohort of 1214 patients. Lupus 2005; 14: 938-946.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Buyon J. P., Wallace D. J. The endocrine system, use of exogenous estrogens, and the urogenaital tract. In: Wallace D. J., Hahn B. N., eds. Dubois' lupus erythematosus. 5-th ed. Baltimore: Williams &amp; Wilkins; 1997. 817-834.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Chang D.-M., Chang C.-C., Kuo S.-Y. et al. Hormonal profiles and immunological studies of male lupus in Taiwan. Clin. Rheumatol. 1999; 18: 158-162.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Hochberg M. C. Epidemiology of systemic lupus erythematosus. In: Wallace D. J., Hahn B. N., eds. Dubois' lupus erythematosus. 5-th ed. Baltimore: Williams &amp; Wilkins; 1997. 49-68.</mixed-citation></ref></ref-list></back></article>
