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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">30266</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Editorial article</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Передовая статья</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Development of theory on intestinal dysfunction in the XXI century</article-title><trans-title-group xml:lang="ru"><trans-title>Pазвитие учения о функциональных pасстpойствах кишечника в XXI веке</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Papfenov</surname><given-names>Asfol'd Ivanovich</given-names></name><name xml:lang="ru"><surname>Паpфенов</surname><given-names>Асфольд Иванович</given-names></name></name-alternatives><bio xml:lang="ru"><p>проф., зам. директора по науке; ГУ Центральный научно-исследовательский институт гастроэнтерологии</p></bio><email>asfold@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Parfenov</surname><given-names>A I</given-names></name><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ГУ Центральный научно-исследовательский институт гастроэнтерологии</institution></aff></aff-alternatives><aff id="aff2"><institution></institution></aff><pub-date date-type="pub" iso-8601-date="2009-02-15" publication-format="electronic"><day>15</day><month>02</month><year>2009</year></pub-date><volume>81</volume><issue>2</issue><issue-title xml:lang="en">NO2 (2009)</issue-title><issue-title xml:lang="ru">ТОМ 81, №2 (2009)</issue-title><fpage>5</fpage><lpage>10</lpage><history><date date-type="received" iso-8601-date="2020-04-09"><day>09</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2009, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2009, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/30266">https://ter-arkhiv.ru/0040-3660/article/view/30266</self-uri><abstract xml:lang="en"><p/></abstract><trans-abstract xml:lang="ru"><p/></trans-abstract><kwd-group xml:lang="en"><kwd>editorial</kwd><kwd>functional intestinal disorders</kwd><kwd>irritable bowel syndrome</kwd><kwd>functional diarrhea</kwd><kwd>functional constipation</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>передовая статья</kwd><kwd>функциональные расстройства кишечника</kwd><kwd>синдром раздраженного кишечника</kwd><kwd>функциональная диарея</kwd><kwd>функциональный запор</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Саркисов Д. 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