<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">30209</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Editorial article</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Передовая статья</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Loop diuretics in the treatment of edema: torasemide potentials</article-title><trans-title-group xml:lang="ru"><trans-title>Петлевые диуретики в лечении отечного синдрома: возможности торасемида</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Fomin</surname><given-names>V V</given-names></name><name xml:lang="ru"><surname>Фомин</surname><given-names>В В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Moiseev</surname><given-names>S V</given-names></name><name xml:lang="ru"><surname>Моисеев</surname><given-names>С В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Russkikh</surname><given-names>A V</given-names></name><name xml:lang="ru"><surname>Русских</surname><given-names>А В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ММА им. И. М. Сеченова</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2008-06-15" publication-format="electronic"><day>15</day><month>06</month><year>2008</year></pub-date><volume>80</volume><issue>6</issue><issue-title xml:lang="en">VOL 80, NO6 ()</issue-title><issue-title xml:lang="ru">ТОМ 80, №6 (2008)</issue-title><fpage>77</fpage><lpage>80</lpage><history><date date-type="received" iso-8601-date="2020-04-09"><day>09</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2008, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2008, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2008</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/30209">https://ter-arkhiv.ru/0040-3660/article/view/30209</self-uri><abstract xml:lang="ru"><p/></abstract><kwd-group xml:lang="en"><kwd>edema</kwd><kwd>loop diuretics</kwd><kwd>torasemid</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>лекция</kwd><kwd>отечный синдром</kwd><kwd>петлевые диуретики</kwd><kwd>торасемид</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Bleich М., Greger R. Mechanism of action of diuretics. Kidney Int. 1997; 51 (suppl. 59): S11-S15.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Suki W. N. Use of diuretics in chronic renal failure. Kidney Int. 1997; 51 (suppl. 59): S33-S35.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Dunn C. J., Fitton A., Brogden R. N. Torasemide. An update of its pharmacological properties and therapeutic efficacy. Drugs 1995; 49 (1): 121-142.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Tesar V., Zima Т., Kalousova M. Pathobiochemistry of nephrotic syndrome. Adv. Clin. Chem. 2003; 37: 173-218.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Friedley H., Buckley M., Torasemide. A review of its pharmacological properties and therapeutic potential. Drugs 1991; 41 (1): 81-103.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Vargo D. L., Kramer W. G., Black P. К. et al. Bioavailability, pharmacokinetics and pharmacodynamics of torasemide and furosemide in patients with congestive heart failure. Clin. Pharmacol. Trier. 1995; 57: 601-609.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Kim E. J., Lee M. G. Pharmacokinetics and pharmacodynamics of intravenous trasemide in mutant Nagase analbuminemic rats. Biopharm. Drug Dispos. 2003; 24 (1): 27-35.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Gerbes A. L., Bertheau-Reitha U., Falkner C. et al. Advantages of the new loop diuretic torasemide over furosemide in patients with cirrhosis and ascites. A randomized, double blind crossover trial. J. Hepatol. 1993; 17 (3): 353-358.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Kramer W. G. Effect of food on the pharmacokinetics and pharmacodynamics of torsemide. Am. J. Ther. 1995; 2 (7): 499-503.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Boesken W. H., Kult J. High-dose torasemide, given once daily intravenously for one week, in patients with advanced chronic renal failure. Clin. Nephrol. 1997; 48 (1): 22-28.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Fliser D., Schroter M., Neubeck M. et al. Coadministration of thiazides increases the efficacy of loop diuretics even in patients with advanced renal failure. Kidney Int. 1994; 46 (2): 482-488.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Gehr T. W., Rudy D. W., Matzke G. R. et al. The pharmacokinetics of intravenous and oral torsemide in patients with chronic renal insufficiency. Clin. Pharmacol. Ther. 1994; 56 (1): 31-38.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Whelton A., Smith W. В., Wallin J. D. et al. Long-term treatment with oral torsemide and its effect on body weight and fluid balance in patients with chronic renal insufficiency. Am. J. Ther. 1996; 3 (11): 743-749.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Risler T., Krämer В., Müller G. A. The efficacy of diuretics in acute and chronic renal failure. Focus on torasemide. Drugs 1991; 41 (suppl. 3): 69-79.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Shilliday I. R., Quinn K. J., Allison M. E. Loop diuretics in the management of acute renal failure: a prospective, double-blind, placebo-controlled, randomized study. Nephrol. Dial. Transplant. 1997; 12 (12): 2592-2596.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Bagshaw S. M., Delaney A., Haase M. et al. Loop diuretics in the management of acute renal failure: a systematic review and meta-analysis. Crit. Care Resusc. 2007; 9 (1): 60-68.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Vargas Hein O., Staegemann M., Wagner D. et al. Torsemide versus furosemide after continuous renal replacement therapy due to acute renal failure in cardiac surgery patients. Ren. Fail. 2005; 27 (4): 385-392.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Vormfelde S. V., Schirmer M., Hagos Y. et al. Torsemide renal clearance and genetic variation in luminal and basolateral organic anion transporters. Br. J. Clin. Pharmacol. 2006; 62 (3): 323-335.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Brater D. C. Benefits and risks of torasemide in congestive heart failure and essential hypertension. Drug Saf. 1996; 14(2)	: 104-120.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Patterson J. H., Adams K. F. Jr., Applefeld M. M. et al. Oral torsemide in patients with chronic congestive heart failure: effects on body weight, edema, and electrolyte excretion. Torsemide Investigators Group. Pharmacotherapy 1994; 14 (5): 514-521.</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Paterna S., Fasullo S., Di Pasquale P. High-dose torasemide is equivalent to high-dose furosemide with hypertonic saline in the treatment of refractory congestive heart failure. Clin. Drug Invest. 2005; 25 (3): 165-173.</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Murray M. D., Deer M. M., Ferguson J. A. et al. Open-label randomized trial of torsemide compared with furosemide therapy for patients with heart failure. Am. J. Med. 2001; 111 (7): 513-520.</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Cosin J., Diet J. TORIC Investigators. Torasemide in chronic heart failure: results of the TORIC study. Eur. J. Heart Fail. 2002; 4 (4): 507-513.</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>Kasama S., Toyama Т., Hatori T. et al. Effects of torasemide on cardiac sympathetic nerve activity and left ventricular remodelling in patients with congestive heart failure. Heart 2006; 92 (10): 1434-1440.</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>Goodfriend T. L., Ball D. L., Oelkers W., Bahr V. Torsemide inhibits aldosterone secretion in vitro. Life Sci. 1998; 63 (3): PL45-PL50.</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>Struthers A. D. Impact of aldosterone on vascular pathophysiology. Congest. Heart Fail. 2002; 8: 18-22.</mixed-citation></ref><ref id="B27"><label>27.</label><mixed-citation>Auchus R. A. Aldo is back: recent advances and unresolved controversies in hyperaldosteronism. Curr. Opin. Nephrol. Hy-pertens. 2003; 12: 153-158.</mixed-citation></ref><ref id="B28"><label>28.</label><mixed-citation>Pitt В., Zannad F., Remme W. J. et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N. Engl. J. Med. 1999; 341: 709-717.</mixed-citation></ref><ref id="B29"><label>29.</label><mixed-citation>Pitt В., Remme W., Zannad F. et al. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N. Engl. J. Med. 2003; 348: 1309-1321.</mixed-citation></ref><ref id="B30"><label>30.</label><mixed-citation>Yamato M., Sasaki Т., Honda M. et al. Effects of torasemide on left ventricular function and neurohumoral factors in patients with chronic heart failure. Circ. J. 2003; 67: 384-390.</mixed-citation></ref><ref id="B31"><label>31.</label><mixed-citation>Lopez В., Querejeta R., Gonzalez A. et al. Effects of loop diuretics on myocardial fibrosis and collagen type I turnover in chronic heart failure. J. Am. Coll. Cardiol. 2004; 43 (11): 2028-2035.</mixed-citation></ref><ref id="B32"><label>32.</label><mixed-citation>Lopez В., Gonzalez A., Beaumont J. et al. Identification of a potential cardiac antifibrotic mechanism of torasemide in patients with chronic heart failure. J. Am. Coll. Cardiol. 2007; 50 (9): 859-867.</mixed-citation></ref><ref id="B33"><label>33.</label><mixed-citation>Veeraveedu P. Т., Watanabe К., Ma M. et al. Comparative effects of torasemide and furosemide in rats with heart failure. Biochem. Pharmacol. 2007; 23: 143-148.</mixed-citation></ref><ref id="B34"><label>34.</label><mixed-citation>Reyes A. J., Leary W. P. Renal excretory responses to single and repeated administration of diuretics in healthy subjects: clinical connotations. Cardiovasc. Drugs Ther. 1993; 7 (suppl. 1): 29-44.</mixed-citation></ref><ref id="B35"><label>35.</label><mixed-citation>Franse L. V., Pahor M., Di Bari M. et al. Hypokalemia associated with diuretic use and cardiovascular events in the Systolic Hypertension in the Elderly Program. Hypertension 2000; 35: 1025-1030.</mixed-citation></ref><ref id="B36"><label>36.</label><mixed-citation>Müller K., Gamba G., Jaquet F. et al. Torasemide vs. furosemide in primary care patients with chronic heart failure NYHA II to IV-efficacy and quality of life. Eur. J. Heart Fail. 2003; 5 (6): 793-801.</mixed-citation></ref><ref id="B37"><label>37.</label><mixed-citation>Stroupe К. Т., Forthofer M. M., Brater D. C., Murray M. D. Healthcare costs of patients with heart failure treated with torasemide or furosemide. Pharmacoeconomics. 2000; 17 (5): 429-440.</mixed-citation></ref><ref id="B38"><label>38.</label><mixed-citation>The ESC Task Force. Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005): The Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology. Eur. Heart J. 2005; 26 (11): 1115-1140.</mixed-citation></ref><ref id="B39"><label>39.</label><mixed-citation>Achhammer I., Metz P. Low dose loop diuretics in essential hypertension. Experience with torasemide. Drugs 1991; 41 (suppl. 3): 80-91.</mixed-citation></ref><ref id="B40"><label>40.</label><mixed-citation>Vasavada N., Saha C., Agarwal R. A double-blind randomized crossover trial of two loop diuretics in chronic kidney disease. Kidney Int. 2003; 64 (2): 632-640.</mixed-citation></ref></ref-list></back></article>
