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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">30002</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Editorial article</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Передовая статья</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Secondary myelodysplastic syndrome in patients with multiple myeloma</article-title><trans-title-group xml:lang="ru"><trans-title>Вторичный миелодиспластический синдром у больных множественной миеломой</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Abdulkadyrov</surname><given-names>К М</given-names></name><name xml:lang="ru"><surname>Абдулкадыров</surname><given-names>К М</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург; Государственное учреждение Российский НИИ гематологии и трансфузиологии МЗ и СР РФ</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gritsaev</surname><given-names>S V</given-names></name><name xml:lang="ru"><surname>Грицаев</surname><given-names>С В</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург; Государственное учреждение Российский НИИ гематологии и трансфузиологии МЗ и СР РФ</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bessmeltsev</surname><given-names>S S</given-names></name><name xml:lang="ru"><surname>Бессмелъцев</surname><given-names>С С</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург; Государственное учреждение Российский НИИ гематологии и трансфузиологии МЗ и СР РФ</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Matynkevich</surname><given-names>I S</given-names></name><name xml:lang="ru"><surname>Мартынкевич</surname><given-names>И С</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург; Государственное учреждение Российский НИИ гематологии и трансфузиологии МЗ и СР РФ</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tiranova</surname><given-names>S A</given-names></name><name xml:lang="ru"><surname>Тиранова</surname><given-names>С А</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург; Государственное учреждение Российский НИИ гематологии и трансфузиологии МЗ и СР РФ</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Blinov</surname><given-names>M N</given-names></name><name xml:lang="ru"><surname>Блинов</surname><given-names>М Н</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург; Государственное учреждение Российский НИИ гематологии и трансфузиологии МЗ и СР РФ</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Stelmashenko</surname><given-names>L V</given-names></name><name xml:lang="ru"><surname>Стельмашенко</surname><given-names>Л В</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург; Государственное учреждение Российский НИИ гематологии и трансфузиологии МЗ и СР РФ</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pesterova</surname><given-names>V V</given-names></name><name xml:lang="ru"><surname>Пестерова</surname><given-names>В В</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург; Государственное учреждение Российский НИИ гематологии и трансфузиологии МЗ и СР РФ</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">Государственное учреждение Российский НИИ гематологии и трансфузиологии МЗ и СР РФ</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2004-07-15" publication-format="electronic"><day>15</day><month>07</month><year>2004</year></pub-date><volume>79</volume><issue>7</issue><issue-title xml:lang="en">NO7 (2004)</issue-title><issue-title xml:lang="ru">ТОМ 79, №7 (2004)</issue-title><fpage>85</fpage><lpage>87</lpage><history><date date-type="received" iso-8601-date="2020-04-09"><day>09</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2004, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2004, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2004</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/30002">https://ter-arkhiv.ru/0040-3660/article/view/30002</self-uri><abstract xml:lang="ru"><p>secondary myelodysplastic syndrome, multiple myeloma, complex karyotype impairments, treatment</p></abstract><kwd-group xml:lang="ru"><kwd>вторичный миелодиспластический синдром</kwd><kwd>множественная миелома</kwd><kwd>комплексные нарушения кариотипа</kwd><kwd>лечение</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Bergsagel D. 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