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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">29899</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Editorial article</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Передовая статья</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Diagnosis of coronary atherosclerosis using stress echocardiography with bicycle exercise</article-title><trans-title-group xml:lang="ru"><trans-title>ДИАГНОСТИКА КОРОНАРНОГО АТЕРОСКЛЕРОЗА С ПОМОЩЬЮ ЭХОКАРДИОГРАФИИС ФИЗИЧЕСКОЙ НАГРУЗКОЙ НА ВЕЛОЭРГОМЕТРЕ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Duplyakov</surname><given-names>D V</given-names></name><name xml:lang="ru"><surname>Дупляков</surname><given-names>Д В</given-names></name></name-alternatives><bio xml:lang="ru"><p>Центр медицины труда АО "АвтоВАЗ", Тольятти; 32-й ЦВМКГ, Москва</p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Emelyanenko</surname><given-names>V M</given-names></name><name xml:lang="ru"><surname>Емельяненко</surname><given-names>В М</given-names></name></name-alternatives><bio xml:lang="ru"><p>Центр медицины труда АО "АвтоВАЗ", Тольятти; 32-й ЦВМКГ, Москва</p></bio><xref ref-type="aff" rid="aff4"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Svetlakova</surname><given-names>L P</given-names></name><name xml:lang="ru"><surname>Светлакова</surname><given-names>Л П</given-names></name></name-alternatives><bio xml:lang="ru"><p>Центр медицины труда АО "АвтоВАЗ", Тольятти; 32-й ЦВМКГ, Москва</p></bio><xref ref-type="aff" rid="aff4"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Goleva</surname><given-names>S V</given-names></name><name xml:lang="ru"><surname>Голева</surname><given-names>С В</given-names></name></name-alternatives><bio xml:lang="ru"><p>Центр медицины труда АО "АвтоВАЗ", Тольятти; 32-й ЦВМКГ, Москва</p></bio><xref ref-type="aff" rid="aff4"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sysuenkova</surname><given-names>E V</given-names></name><name xml:lang="ru"><surname>Сысуенкова</surname><given-names>Е В</given-names></name></name-alternatives><bio xml:lang="ru"><p>Центр медицины труда АО "АвтоВАЗ", Тольятти; 32-й ЦВМКГ, Москва</p></bio><xref ref-type="aff" rid="aff4"/><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">Центр медицины труда АО "АвтоВАЗ", Тольятти</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="ru">32-й ЦВМКГ, Москва</institution></aff><aff><institution xml:lang="en"></institution></aff></aff-alternatives><aff id="aff3"><institution>32-й ЦВМКГ, Москва</institution></aff><aff id="aff4"><institution>Центр медицины труда АО "АвтоВАЗ", Тольятти</institution></aff><pub-date date-type="pub" iso-8601-date="2004-11-15" publication-format="electronic"><day>15</day><month>11</month><year>2004</year></pub-date><volume>79</volume><issue>11</issue><issue-title xml:lang="en">NO11 (2004)</issue-title><issue-title xml:lang="ru">ТОМ 79, №11 (2004)</issue-title><fpage>14</fpage><lpage>19</lpage><history><date date-type="received" iso-8601-date="2020-04-09"><day>09</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2004, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2004, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2004</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/29899">https://ter-arkhiv.ru/0040-3660/article/view/29899</self-uri><abstract xml:lang="en"><p>Aim. To determine sensitivity and specificity of stress echocardiography (SEC) in diagnosis of stenosing atherosclerosis of coronary arteries (CA), especially in patients recovered from Q-myocardial infarction.
Material and methods. The above sensitivity and specificity were studied in 75 patients (70 males and
5 females; mean age 53.7 ± 7 years) with coronary atherosclerosis (CS).
Results. The sensitivity of impaired local contractility index (IL CI) in univessel lesion was 77.8%, in
multivessel lesion - 90.4%, specificity - 85.7%. Sensitivity of other parameters studied was for development of an anginal episode 65.4%, increment of ejection fraction under 5% - 63.9%, increased
end systolic volume - 61.1 %, depression of ST segment - 48.1 %, increased end diastolic volume
38.9%. A total of 3 parameters had 100% sensitivity: impossible a &gt; 5% rise of EF in response to exercise, an increase of end systolic and diastolic volumes, anginal attack (85.7%), ST depression
(78.6%).
Conclusion. Hemodynamic parameters must be assessed in the course of SECG for objectiviiation of
the result and improvement of its specificity.</p></abstract><trans-abstract xml:lang="ru"><p>Цель исследования. Определить чувствительность и специфичность нагрузочной эхокардиографии (НЭхоКГ) с велоэргометрией (ВЭМ) в диагностике стенозирующего атеросклероза коронарных артерий (КА), особенно у пациентов, перенесших ранее инфаркт миокарда с зубцом Q.
Материалы и методы. Обследовали 75 пациентов (70 мужчин и 5 женщин; средний возраст
53,7 ± 7 лет) с коронарным атеросклерозом.
Результаты. Чувствительность индекса нарушения локальной сократимости при однососудистом поражении составила 77,8%, при многосуточном - 90,4%, специфичность - 85,7%.
Чувствительность других изучавшихся параметров составила для развития приступа стенокардии 65,4%, прироста фракции (ФВ менее 5) 63,9%, увеличения конечного систолического
объема (КСО) 61,1%, снижения сегмента ST 48,1%, увеличения конечного диастолического
объема (КДО) 38,9. При оценке специфичности выявлено, что сразу 3 параметра обладали
специфичностью 100%: невозможность прироста ФВ более 5% в ответ на физическую нагрузку, увеличение КСО и КДО, затем ангиозный приступ 85,7% и на последнем месте - снижение сегмента ST 78,6%.
Заключение. Полученные результаты указывают на обязательность оценки гемодинамических параметров во время проведения НЭхоКГ для объективизации результата и повышения
его специфичности.</p></trans-abstract><kwd-group xml:lang="en"><kwd>stress echocardiography</kwd><kwd>ischemic heart disease</kwd><kwd>myocardial infarction</kwd><kwd>hemodynamics</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>нагрузочная эхокардиография</kwd><kwd>ишемическая болезнь сердца</kwd><kwd>инфаркт миокарда</kwd><kwd>гемодинамика</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>ACC/AHA guidelines for the clinical application of echocardiography: Executive summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Clinical Application of Echocardiography). Developed in collaboration with the American Society of Echocardiography. J. Am. Coll. Cardiol. 1997; 29: 862-879.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Cortigiani L., Lombardi M., Landi P. et al. Risk stratification bv pharmacological stress echocardiography in a primary care cardiology center. Eur. Heart J. 1998; 19: 1673-1680.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Pasierski Т., Szwed H., Malczewska B. et al. Advantages of exercise echocardiography in comparison to dobutamine echocardiography in the diagnosis of coronary artery disease in hypertensive subjects. J. Hum. Hypertens. 2001; 15(11): 805- 809.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Marangelli V., fliceto S., Piccinni G. et al. Detection of coronary artery disease by digital stress echocardiography: comparison of exercise, transesophageal atrial pacing and dipyridamole echocardiography. J. Am. Coll. Cardiol. 1994; 24 (1): 117-124.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Roger V. L., Pellikka P. A., Oh J. K. et al. Stress echocardiography. Part I. Exercise echocardiography: techniques, implementation, clinical applications, and correlation. Mayo Clin. Proc. 1995; 80 (1): 5-15.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Feigenbaum H. Stress echocardiography. Cardiovasc. Imag. 1992; 4 (1): 13-18.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Ботвин И. М., Кострова В. В., Атьков О. Ю. Нагрузочная эхокардиография. I: методологические основы. Визуализация в клинике 1997; 10: 54-60.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Armstrong W. F., O'Donnell J., Ryan Т., Feigenbaum H. Effect of prior myocardial infarction and extent and location of coronary disease on accuracy of exercise echocardiography. J. Am. Coll. Cardiol. 1987; 10: 531-538.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Beleslin B. D., Ostojic M., Stepanovic J. et al. Stress echocardiography in the detection of myocardial ischemia. Head-tohead comparison of exercise, dobutamine, and dipyridamole tests. Circulation 1994; 90: 1168-1176.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Crouse L. J., Harbrecht J. J., Vacek J. L. et al. Exercise echocardiography as a screening test for coronary artery disease and correlation with coronary arteriography. Am. J. Cardiol. 1991; 67: 1213-1218.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Hecht H. S., DeBord L., Shaw R. et al. Digital supine bicycle stress echocardiography: a new technique for evaluating coronary artery disease. J. Am. Coll. Cardiol. 1993; 21: 950-956.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Marwick Т. Н., Nemec J. J., Pashkow F. J. et al. Accuracy and limitations of exercise echocardiography in a routine clinical setting. J. Am. Coll. Cardiol. 1992; 19: 74-81.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Quinones M. A., Verani M. S., Halchln R. M. et al. Exercise echocardiography versus 201T1 single-photon emission computed tomography in evaluation of coronary artery disease. Analysis of 292 patients. Circulation 1992;.85: 1026-1031.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Roger V. L., Pellikka P. A., Oh J. K. et al. Identification of multivessel coronary artery disease by exercise echocardiography. J. Am. Coll. Cardiol. 1994; 24: 109-114.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Ryan Т., Segar D. S., Sawada S. G. et al. Detection of coronary artery disease with upright bicycle exercise echocardiography. J. Am. Soc. Echocardiogr. 1993; 6: 186-197.</mixed-citation></ref></ref-list></back></article>
