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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">109636</article-id><article-id pub-id-type="doi">10.26442/00403660.2022.07.201732</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Seх differences in treatment of acute coronary syndrome patients. Data from federal registry of acute coronary syndrome 2016–2019</article-title><trans-title-group xml:lang="ru"><trans-title>Гендерные различия в оказании медицинской помощи при остром коронарном синдроме. Анализ данных Федерального регистра острого коронарного синдрома за 2016–2019 гг.</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2534-8463</contrib-id><name-alternatives><name xml:lang="en"><surname>Sagaydak</surname><given-names>Olesya V.</given-names></name><name xml:lang="ru"><surname>Сагайдак</surname><given-names>Олеся Владимировна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>канд. мед. наук, науч. сот. отд. гипертонии</p></bio><email>olesyasagaydak@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4534-9890</contrib-id><name-alternatives><name xml:lang="en"><surname>Oschepkova</surname><given-names>Elena V.</given-names></name><name xml:lang="ru"><surname>Ощепкова</surname><given-names>Елена Владимировна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>д-р мед. наук, проф., рук. отд. координации и мониторинга научных программ</p></bio><email>olesyasagaydak@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9822-4357</contrib-id><name-alternatives><name xml:lang="en"><surname>Chazova</surname><given-names>Irina E.</given-names></name><name xml:lang="ru"><surname>Чазова</surname><given-names>Ирина Евгеньевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>акад. РАН, д-р мед. наук, проф., зам. ген. дир. по научно-экспертной работе</p></bio><email>olesyasagaydak@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Chazov National Medical Research Center of Cardiology</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр кардиологии им. акад. Е.И. Чазова» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2022-08-12" publication-format="electronic"><day>12</day><month>08</month><year>2022</year></pub-date><volume>94</volume><issue>7</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>797</fpage><lpage>802</lpage><history><date date-type="received" iso-8601-date="2022-08-05"><day>05</day><month>08</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-08-05"><day>05</day><month>08</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/109636">https://ter-arkhiv.ru/0040-3660/article/view/109636</self-uri><abstract xml:lang="en"><p><bold>Introduction.</bold> Management of patients with acute coronary syndrome (ACS) is usually universal, regardless of gender, age, and ethnicity. But often in practice, gender and age influence medical decisions, and patients do not receive proper medical care. Medical care for patients with ACS was analyzed by gender according to the federal register of ACS data.</p> <p><bold>Aim. </bold>To analyze the influence of the patient's gender on the course of the disease and on the provision of medical care to patients with ACS who underwent treatment in 2016–2019.</p> <p><bold>Materials and methods. </bold>The data of 95 586 cases was analyzed. Two groups were identified: men (<italic>n=</italic>59 442, 62.2%) and women (<italic>n=</italic>36 144, 57.8%).</p> <p><bold>Results.</bold> Anamnesis analysis has revealed, that women were often more burdened with concomitant diseases and had a higher risk on the GRACE scale at admission. It was demonstrated that men underwent revascularization on average significantly more often than women (51.9% versus 32.5%, respectively, <italic>p&lt;</italic>0.001). In women, conservative therapy was more. When compared with the appropriate use criteria for coronary revascularization, it was shown that more than 70% of women in whom a conservative treatment strategy was chosen, it was expedient to undergo myocardial revascularization using percutaneous coronary intervention.</p> <p><bold>Conclusion.</bold> Gender differences were revealed in the course of the disease, as well as in the choice of treatment by doctors. Women are characterized by a later manifestation of the disease, more often in the form of <italic>ST</italic>-ACS. The course of the disease in women is associated with a higher comorbidity, atypical symptoms and later call for help. A conservative approach prevails in the choice of ACS treatment tactics in women.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Введение. </bold>Тактика ведения больных с острым коронарным синдромом (ОКС) практически универсальна вне зависимости от пола, возраста и этнических принадлежностей. Однако зачастую на практике пол и возраст влияют на принятие врачебного решения, и пациенты не получают медицинскую помощь в полном объеме. По данным Федерального регистра ОКС проанализирована медицинская помощь пациентам с ОКС в разрезе половой принадлежности.</p> <p><bold>Цель. </bold>Проанализировать влияние пола пациента на течение заболевания и оказание медицинской помощи больным с ОКС, прошедших лечение в 2016–2019 гг.</p> <p><bold>Материалы и методы. </bold>Проанализированы данные регистра ОКС по 95 586 историям болезни. Выделено 2 группы: мужчины (<italic>n=</italic>59 442, 62,2%) и женщины (<italic>n=</italic>36 144, 57,8%).</p> <p><bold>Результаты. </bold>При анализе анамнеза пациентов выявлено, что женщины зачастую более отягощены сопутствующими заболеваниями и имели более высокий риск по шкале GRACE при поступлении. Продемонстрировано, что мужчинам реваскуляризация в среднем проводилась достоверно чаще, чем женщинам (51,9% против 32,5% соответственно, <italic>p&lt;</italic>0,001). У женщин чаще тактикой выбора была медикаментозная терапия. При сопоставлении с критериями целесообразности реваскуляризации показано, что более чем 70% женщин, у которых была выбрана консервативная тактика лечения, было целесообразно провести реваскуляризацию миокарда при помощи чрескожного коронарного вмешательства.</p> <p><bold>Заключение. </bold>Выявлены различия в течении заболевания в зависимости от пола, а также в выборе тактики лечения врачами. Для женщин характерна более поздняя манифестация заболевания, чаще в виде ОКС без подъема сегмента <italic>ST</italic>. Особенность течения заболевания у женщин связана с более высокой коморбидностью пациенток с ОКС, атипичной картиной заболевания, более поздним обращением. В выборе тактики лечения превалирует консервативный подход.</p></trans-abstract><kwd-group xml:lang="en"><kwd>register</kwd><kwd>acute coronary syndrome</kwd><kwd>percutaneous coronary intervention</kwd><kwd>sex differences</kwd><kwd>gender differences</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>регистр</kwd><kwd>острый коронарный синдром</kwd><kwd>чрескожное коронарное вмешательство</kwd><kwd>половые различия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Ощепкова Е.В., Сагайдак О.В., Чазова И.Е. Особенности лечения острого коронарного синдрома у пациентов старческого возраста (по данным Федерального регистра острого коронарного синдрома). Терапевтический архив. 2018;3(90):67-71 [Oschepkova EV, Sagaydak OV, Chazova IE. Management of acute coronary syndrome in older adults (data from Russian federal acute coronary syndrome registry). Terapevticheskii Arkhiv (Ter. 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