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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Terapevticheskii arkhiv</journal-id><journal-title-group><journal-title xml:lang="en">Terapevticheskii arkhiv</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапевтический архив</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0040-3660</issn><issn publication-format="electronic">2309-5342</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">104687</article-id><article-id pub-id-type="doi">10.26442/00403660.2022.01.201316</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The prevalence of anemia and its associations with other geriatric syndromes in subjects over 65 years old: data of Russian epidemiological study EVKALIPT</article-title><trans-title-group xml:lang="ru"><trans-title>Распространенность анемии и ее ассоциации с другими гериатрическими синдромами у лиц старше 65 лет: данные российского эпидемиологического исследования ЭВКАЛИПТ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3066-4866</contrib-id><name-alternatives><name xml:lang="en"><surname>Khovasova</surname><given-names>Natalia O.</given-names></name><name xml:lang="ru"><surname>Ховасова</surname><given-names>Наталья Олеговна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>канд. мед. наук, доц., ст. науч. сотр. лаб. заболеваний костно-мышечной системы, доц. каф. болезней старения ФГАОУ ВО «РНИМУ им. Н.И. Пирогова»</p></bio><email>natashahov@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6021-7864</contrib-id><name-alternatives><name xml:lang="en"><surname>Vorobyeva</surname><given-names>Natalya M.</given-names></name><name xml:lang="ru"><surname>Воробьева</surname><given-names>Наталья Михайловна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>д-р мед. наук, зав. лаб. сердечно- сосудистого старения</p></bio><email>natashahov@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4193-688X</contrib-id><name-alternatives><name xml:lang="en"><surname>Tkacheva</surname><given-names>Olga N.</given-names></name><name xml:lang="ru"><surname>Ткачева</surname><given-names>Ольга Николаевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>д-р мед. наук, проф., дир. ОСП РГНКЦ ФГАОУ ВО «РНИМУ им. Н.И. Пирогова», зав. каф. болезней старения ФГАОУ ВО «РНИМУ им. Н.И. Пирогова», глав. внешт. гериатр Минздрава России</p></bio><email>natashahov@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1628-5093</contrib-id><name-alternatives><name xml:lang="en"><surname>Kotovskaya</surname><given-names>Yulia V.</given-names></name><name xml:lang="ru"><surname>Котовская</surname><given-names>Юлия Викторовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>д-р мед. наук, проф., зам. дир. по научной работе ОСП РГНКЦ ФГАОУ ВО «РНИМУ им. Н.И. Пирогова»</p></bio><email>natashahov@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Naumov</surname><given-names>Anton V.</given-names></name><name xml:lang="ru"><surname>Наумов</surname><given-names>Антон Вячеславович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>д-р мед. наук, проф. каф. болезней старения ФДПО, зав. лаб. заболеваний костно-мышечной системы ОСП РГНКЦ ФГАОУ ВО «РНИМУ им. Н.И. Пирогова»</p></bio><email>natashahov@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6623-6815</contrib-id><name-alternatives><name xml:lang="en"><surname>Selezneva</surname><given-names>Elena V.</given-names></name><name xml:lang="ru"><surname>Селезнева</surname><given-names>Елена Владимировна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>канд. экон. наук, ст. науч. сотр.</p></bio><email>natashahov@mail.ru</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7266-707X</contrib-id><name-alternatives><name xml:lang="en"><surname>Ovcharova</surname><given-names>Lilia N.</given-names></name><name xml:lang="ru"><surname>Овчарова</surname><given-names>Лилия Николаевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>д-р экон. наук, проректор</p></bio><email>natashahov@mail.ru</email><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Russian Clinical and Research Center of Gerontology</institution></aff><aff><institution xml:lang="ru">ОСП «Российский геронтологический научно-клинический центр» ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Pirogov Russian National Research Medical University</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">National Research University “Higher School of Economics”</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО «Национальный исследовательский университет “Высшая школа экономики”»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2022-01-15" publication-format="electronic"><day>15</day><month>01</month><year>2022</year></pub-date><volume>94</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>24</fpage><lpage>31</lpage><history><date date-type="received" iso-8601-date="2022-03-10"><day>10</day><month>03</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-03-10"><day>10</day><month>03</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ter-arkhiv.ru/0040-3660/article/view/104687">https://ter-arkhiv.ru/0040-3660/article/view/104687</self-uri><abstract xml:lang="en"><p><bold>Background. </bold>A low hemoglobin level in older adults impairs cognitive ability and functional status and associates with risk of falls and fractures, sarcopenia, malnutrition, depression, frailty, and decreased autonomy. Epidemiological data on the anemia prevalence in the geriatric population in our country is not available.</p> <p><bold>Aim.</bold> To assess the prevalence of anemia and analyze its associations with geriatric syndromes (GS) in subjects aged ≥65 years.</p> <p><bold>Materials and methods. </bold>4308 subjects (30% of men) aged 65–107 years, living in 11 regions of the Russian Federation, were examined and divided into age groups (65–74 years, 75–84 years and ≥85 years). All the participants underwent a comprehensive geriatric assessment and determined hemoglobin level.</p> <p><bold>Results. </bold>The anemia prevalence in older adults was 23.9%. It has been shown that with an increase in age per 1 year, the risk of anemia detection increases by 4%. The incidence of anemia was higher in males than females (28.1% versus 22.1%; <italic>p</italic>&lt;0.001). In most cases, anemia was mild. The results of a comprehensive geriatric assessment show that patients with anemia had lower hand grip force, Barthel Index, the sum of points on Lawton instrumental activities of daily living scale, Mini Nutritional Assessment scale, the Mini-Cog test and higher – the sum of points on the Geriatric Depression Scale (GDS-15) and the Age Is No Barrier scale. Patients with anemia were more likely to use hearing aids, absorbent underwear, and assistive devices during movement. Patients with anemia had a higher incidence of all GS, except for orthostatic hypotension and chronic pain syndrome. The presence of GS is associated with an increased risk of anemia by 1.3–3.4 times.</p> <p><bold>Conclusion.</bold> EVKALIPT study obtained domestic data on the prevalence of anemia in older patients and examined its associations with other GS.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Обоснование. </bold>Снижение гемоглобина у людей пожилого возраста ухудшает функциональный и когнитивный статусы, ассоциируется с риском падений и переломов, саркопенией, мальнутрицией, депрессией, старческой астенией и снижением автономности. Эпидемиологических данных о распространенности анемии в гериатрической популяции в нашей стране нет.</p> <p><bold>Цель. </bold>Оценить распространенность анемии и проанализировать ее ассоциации с гериатрическими синдромами (ГС) у лиц в возрасте ≥65 лет.</p> <p><bold>Материалы и методы. </bold>Обследованы 4308 человек (30% мужчин) в возрасте от 65 до 107 лет, проживающих в 11 регионах Российской Федерации, которых распределили на возрастные группы (65–74 года, 75–84 года и ≥85 лет). Всем участникам выполнена комплексная гериатрическая оценка и определен гемоглобин.</p> <p><bold>Результаты.</bold> Распространенность анемии у пожилых людей составила 23,9%. Показано, что при повышении возраста на каждый 1 год риск выявления анемии увеличивается на 4%. Частота анемии оказалась выше у мужчин, чем у женщин (28,1% против 22,1%; <italic>р</italic>&lt;0,001). В большинстве случаев анемия имела легкое течение. По результатам комплексной гериатрической оценки у пациентов с анемией были ниже сила сжатия кисти, величина индекса Бартела, сумма баллов по шкале Лоутона, шкале MNA, тесту Мини-Ког и выше – сумма баллов по Гериатрической шкале депрессии и шкале «Возраст не помеха». Пациенты с анемией чаще пользовались слуховым аппаратом, абсорбирующим бельем и вспомогательными средствами при движении. У пациентов с анемией была выше частота всех ГС, за исключением ортостатической гипотензии и хронического болевого синдрома. Наличие ГС ассоциируется с увеличением риска анемии в 1,3–3,4 раза.</p> <p><bold>Заключение. </bold>В исследовании ЭВКАЛИПТ получены отечественные данные о распространенности анемии у пожилых пациентов и изучены ассоциации между низким гемоглобином и ГС.</p></trans-abstract><kwd-group xml:lang="en"><kwd>anemia</kwd><kwd>geriatric syndrome</kwd><kwd>comprehensive geriatric assessment</kwd><kwd>advanced age</kwd><kwd>functional status</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>анемия</kwd><kwd>гериатрический синдром</kwd><kwd>комплексная гериатрическая оценка</kwd><kwd>пожилой возраст</kwd><kwd>функциональный статус</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Perkins S. Diagnosis of Anemia. In: Kjeldsberg CR ed. Practical Diagnosis of Hematologic Disorders. 4th ed. 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